Cdc42 - the centre of polarity

By Sandrine Étienne-Manneville. Journal of Cell Science, 2004

807 citations recorded by the source corpus.

Subfields: Cell Biology, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/61b19a6abe0bdce4528172d4a205dcfca85da3af

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Citations in the corpus

Manipulation of thyroid status and/or GH injection alters hepatic gene expression in the juvenile chicken (2007, background): “CDC42EP1 is a binding protein, which inactivates CDC42, a major GTPase that regulates cell polarity, motility and proliferation (Schmitz et al., 2000; Burridge and Wennerberg, 2004; Etienne-Manneville, 2004; Jaffe and Hall, 2005; Fidyk et al., 2006).”
Microtubule assembly, organization and dynamics in axons and dendrites (2009, background): “In several non-neuronal cells the centrosome and the Golgi apparatus (GA) are reoriented to a position between the leading edge and the nucleus during polarized migratio”
Random versus directionally persistent cell migration (2009, background): “The Rho GTPase family member CDC42 is a master regulator of cell polarization that influences directional migratio”
Nuclear movement regulated by Cdc42, MRCK, myosin, and actin flow establishes MTOC polarization in migrating cells. (2005, neutral): “Our results do not support previous models that propose that the MTOC moves to a position between the nucleus and the leading edge during MTOC reorientation (Schliwa and Honer, 1993; Gundersen, 2002; Etienne-Manneville, 2004).”
Rho GTPase signalling in cell migration (2015, background): “Cdc42 can localize Rac activity through multiple potentially synergistic pathways including microtubule capture at the leading edge, RacGEF localization and directed vesicle trafficking [39].”
Controlling NK Cell Responses: Integration of Signals for Activation and Inhibition (2013, background): “The small Rho family GTPase Cdc42 is a key control element in cell polarity (101).”
Mammalian Rho GTPases: new insights into their functions from in vivo studies (2008, background): “Cdc42 was first identified in Saccharomyces cerevisiae as a cell-cycle mutant; loss of Cdc42 prevents budding and mating projectio”