Shifting the balance: antibiotic effects on host–microbiota mutualism

By B. Willing, Shannon L. Russell, B. B. Finlay. Nature Reviews Microbiology, 2011

741 citations recorded by the source corpus.

Subfields: Dermatology, Infectious Diseases, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/60c29d0f17f8c67ae0e4b8ed90627642235fdf73

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In Infectious Diseases

In Molecular Biology

Citations in the corpus

How bacterial pathogens colonize their hosts and invade deeper tissues. (2015, background): “Many studies are now highlighting that the composition of this microbiota may be 529 altered by various external parameters including overuse of antibiotics, changes in diet and 530 elimination of constitutive partners such as nematodes [96],[97].”
The Hologenome Concept: Human, Animal and Plant Microbiota (2014, background): “Willing et al. (2011) have reviewed the effects of different antibiotics on host-microbiota mutualism.”
Impact of antibiotics on the human microbiome and consequences for host health (2022, background): “Antibiotic use results in a reduction of these bacteria and hence the PRRs such as TLR signaling and downstream regulation of innate defenses (Willing et al., 2011).”
Reduced Incidence of Prevotella and Other Fermenters in Intestinal Microflora of Autistic Children (2013, background): “Several studies have reported an increased administration of oral antibiotics to autistic children during the first 3 years of life [6–8], which may destabilize microbial community by eliminating beneficial bacteria and helping pathogenic bacteria colonize the intestinal walls [9].”
Early life antibiotic‐driven changes in microbiota enhance susceptibility to allergic asthma (2012, neutral): “Antibiotics have the ability to create global shifts in microbial communities, and are valuable tools for studying how changes in the gut microbiota influence disease states [19].”
Microbiota Transfer Therapy alters gut ecosystem and improves gastrointestinal and autism symptoms: an open-label study (2017, background): “Many children with ASD often undergo increased oral antibiotic treatment during the first 3 years of life [11], which is thought to destabilize their gut microbiota [12] and open opportunities for competitive potential pathogens to contribute to ASD severity [13, 14].”
Breaking down the barriers: the gut microbiome, intestinal permeability and stress-related psychiatric disorders (2015, background): “Several enteric pathogens have been shown to have a detrimental effect on the intestinal barrier (Paesold et al., 2002; Berkes et al., 2003; Flynn and Buret, 2008) which can occur via paracellular (Ferrier et al., 2003; Wu et al., 2011) or transcellular routes (Kalischuk et al., 2009).”