Biphasic calcium phosphate bioceramics: preparation, properties and applications

By R. Legeros, S. Lin, R. Rohanizadeh, D. Mijares, J. Legeros. Journal of materials science. Materials in medicine, 2003

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Calcium Orthophosphates in Nature, Biology and Medicine (2009, background): “The BCP concept is determined by the optimum balance of a more stable phase of HA and a more soluble TCP. General requirements for the ideal bone grafts are as follows: pores of some 100 µm size, a biodegradation rate comparable to the formation of bone tissue (i.e., between a few months and about t”
Bioactive Glass and Glass-Ceramic Scaffolds for Bone Tissue Engineering (2010, background): “Bioactive glasses can also serve as vehicle for the local delivery of selected ions being able to control specific cell functions [30,57-64].”
How useful is SBF in predicting in vivo bone bioactivity? (2006, background): “Apatite/b-tricalcium phosphate biphasic ceramic was also found to have an apatite layer form on its surface in SBF [4] and was confirmed to bond to living bone through the apatite layer in vivo [4].”