Calcium Orthophosphates in Nature, Biology and Medicine
By S. Dorozhkin. Materials, 2009
754 citations recorded by the source corpus.
The present overview is intended to point the readers’ attention to the important subject of calcium orthophosphates. These materials are of the special significance because they represent the inorganic part of major normal (bones, teeth and dear antlers) and pathological (i.e. those appearing due to various diseases) calcified tissues of mammals. Due to a great chemical similarity with the biological calcified tissues, many calcium orthophosphates possess remarkable biocompatibility and bioactivity. Materials scientists use this property extensively to construct artificial bone grafts that are either entirely made of or only surface-coated with the biologically relevant calcium ortho-phosphates. For example, self-setting hydraulic cements made of calcium orthophosphates are helpful in bone repair, while titanium substitutes covered by a surface layer of calcium orthophosphates are used for hip joint endoprostheses and as tooth substitutes. Porous scaffolds made of calcium orthophosphates are very promising tools for tissue engineering applications. In addition, technical grade calcium orthophosphates are very popular mineral fertilizers. Thus ere calcium orthophosphates are of great significance for humankind and, in this paper, an overview on the current knowledge on this subject is provided.
Subfields: Biomaterials, Biomedical Engineering, Surgery
View Paper: https://www.semanticscholar.org/paper/6daa52ac34f1fe9a5f25a51bb4687c2c77f12c84
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Citations in the corpus
- Research of Calcium Phosphates Using Fourier Transform Infrared Spectroscopy (2012, background): “Calcium phosphates that are most frequently used in the biomaterial field are demonstrated in Table 1 (Dorozhkin, 2009c; El Kady, 2009; Shi, 2006).”
- Calcium orthophosphates (2011, neutral): “The names, standard abbreviations, chemical formulae and solubility values are listed in Table 1.(29,30) Since all of them”
- Calcium Phosphate Bioceramics: A Review of Their History, Structure, Properties, Coating Technologies and Biomedical Applications (2017, methodology): “As a first approximation, CDHA may be considered as HAp with some ions missing [359].”
- Bioceramics of calcium orthophosphates. (2010, background): “The complete list of known calcium orthophosphates, including their standard abbreviations and the major properties, is given in Table 1, while the detailed information on calcium orthophosphates, their synthesis, structure, chemistry, other properties and biomedical application has been comprehensi”
- Nanoscale hydroxyapatite particles for bone tissue engineering. (2011, background): “Common uses include bone repair, bone augmentation, as well as coating of implants or acting as fillers in bone or teeth [12–18].”