Epidermal homeostasis: a balancing act of stem cells in the skin

By C. Blanpain, Elaine Fuchs. Nature reviews. Molecular cell biology, 2009

1,287 citations recorded by the source corpus.

Subfields: Cell Biology, Molecular Biology, Urology

View Paper: https://www.semanticscholar.org/paper/5f60334b06471fdf4adaac3b7f05e43da478df78

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Cell Biology

1. S. Piccolo
2. C. Blanpain
3. P. Comoglio
4. Livio Trusolino

In Molecular Biology

1. P. Comoglio
2. Livio Trusolino
3. S. Piccolo
4. Bert Vogelstein
5. C. Blanpain
6. J. Rock
7. Masafumi Inui
8. Graziano Martello

In Urology

1. C. Blanpain
2. Elaine Fuchs

Citations in the corpus

• MET signalling: principles and functions in development, organ regeneration and cancer (2010, background): “At the wound edges, marginal keratinocytes form the so-called hyperproliferative epithelium, which undergoes rounds of cell division to provide fresh elements that migrate over the provisional matrix of the injured dermis and repopulate the wounded are”
• Distinct stem cells contribute to mammary gland development and maintenance (2011, background): “For example, hair follicle bulge stem cells give rise to all epidermal lineages upon transplantation and wound healing, but only to hair follicle regeneration under physiological condition”
• Wound repair and regeneration: Mechanisms, signaling, and translation (2014, neutral): “To date, epidermal stem cells of the skin have been shown to occupy at least three distinct niches: the bulge of the hair follicle, the base of the sebaceous gland, and the basal layer of the epidermis (42).”
• MicroRNA control of signal transduction (2010, background): “As cells move suprabasally , they embark on a terminal differentiation programm”
• Variation in cancer risk among tissues can be explained by the number of stem cell divisions (2015, background): “The basal layer is found both around the hair follicles as well as in the interfollicular epidermis (25).”
• The international workshop on meibomian gland dysfunction: report of the subcommittee on anatomy, physiology, and pathophysiology of the meibomian gland. (2011, background): “In wounding conditions, stem cell differentiation tends to develop a higher degree of plasticity,(74) and the lineage commitment can switch, leading to a replacement of altered or lost progenitor cells.(82,88) This process may also apply to events observed in MGD that may exert stress on the cells, ”
• Extracellular matrix: A dynamic microenvironment for stem cell niche (2014, neutral): “(catagen), and rest (telogen) [144,145].”
• Regulatory T cells in Skin Facilitate Epithelial Stem Cell Differentiation (2017, neutral): “A classic function of HFSCs is to drive HF cycling and HF regeneration (Blanpain and Fuchs, 2009; Morris et al., 2004; Trempus et al., 2003).”