MicroRNA control of signal transduction
By Masafumi Inui, Graziano Martello, S. Piccolo. Nature reviews. Molecular cell biology, 2010
1,269 citations recorded by the source corpus.
Subfields: Cancer Research, Molecular Biology
View Paper: https://www.semanticscholar.org/paper/1542020fb58b7854318594e68a8eafdb34ed8c1a
How researchers see this paper
The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.
In Cancer Research
- Anthony Kar Lun Leung
- Phillip A. Sharp
- S. Piccolo
- Yuan Zhou
- Juan Wang
- Qinghua Cui
- Graziano Martello
- Zhan Tong
In Molecular Biology
- S. Piccolo
- Anthony Kar Lun Leung
- Phillip A. Sharp
- M. Cordenonsi
- Antonio Rosato
- Yuan Zhou
- Juan Wang
- Qinghua Cui
Citations in the corpus
- The 'ins' and 'outs' of podosomes and invadopodia: characteristics, formation and function (2011, neutral): “miRNAs are highly conserved small RNAs that inhibit gene expression, either by inhibiting translation or by inducing degradation of target mRNAs, and control pathways that are involved in development, tumour growth and metastasi”
- Wnt/β-catenin signalling: function, biological mechanisms, and therapeutic opportunities (2022, background): “By pairing the 3′untranslated regions (3′-UTRs) of target mRNAs, microRNAs participate in the regulation of Wnt/β-catenin signalling, and different miRNAs have different effects on the Wnt/β-catenin signalling pathway.(41,42) Some miRNAs enhance the Wnt/β-catenin pathway by inhibiting the negative r”
- TransmiR v2.0: an updated transcription factor-microRNA regulation database (2018, background): “As important regulators of gene expression, miRNAs play crucial roles in a variety of biological processes, such as development, cell proliferation, differentiation, apoptosis and cellular signaling (2,3).”
- MicroRNA Functions in Stress Responses (2010, positive): “They are highly dynamic and nonstoichiometric in nature, thus making them particularly sensitive to changes in concentration of thei components (reviewed in Inui et al., 2010).”
- A MicroRNA targeting dicer for metastasis control. (2010, background): “In contrast, the gene network controlling the maintenance of the epithelial phenotype appears mainly under positive control by miRNAs, as attested by multiple miRNAs inhibiting EMT (miR-200a, miR-200b, miR-200c, miR-141, miR-429, miR-205, and miR-125a) (Inui et al., 2010; Polyak and Weinberg, 2009).”
- Cellular and molecular mechanisms of renal fibrosis (2011, background): “Such signal transduction cascades and expression of matrix genes are also regulated by a variety of microRNAs”