Hematopoietic stem cells differentiate into vascular cells that participate in the pathogenesis of atherosclerosis

By M. Sata, A. Saiura, A. Kunisato, A. Tojo, S. Okada, T. Tokuhisa, H. Hirai, M. Makuuchi, Y. Hirata, R. Nagai. Nature Medicine, 2002

1,241 citations recorded by the source corpus.

Subfields: Immunology

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Hemodialysis vascular access dysfunction: a cellular and molecular viewpoint. (2006, background): “(43) have shown that up to 60% of both endothelial and smooth muscle cells within the lesion of neointimal hyperplasia after femoral angioplasty are bone marrow-derived cells.”
The multifaceted contributions of leukocyte subsets to atherosclerosis: lessons from mouse models (2008, background): “Complementary studies in chimeric mice have revealed that bone-marrow-derived SPCs that give rise to SMCs are involved in neointimal growth after arterial injury and are proportional to the degree of damage in transplant arteriopath”
Smooth muscle cell phenotypic switching in atherosclerosis. (2012, background): “HSC lineage-tracing studies were compromised by poor resolution of images and failure to validate markers present in individual cells Sata et al.(34)”
Dual role of matrix metalloproteinases (matrixins) in intimal thickening and atherosclerotic plaque rupture. (2005, background): “(stem cells) that have invaded the plaque (44, 118, 235).”
Vascular proliferation and atherosclerosis: New perspectives and therapeutic strategies (2002, neutral): “[12] [13] [14] [15-18]”