Parahippocampal and retrosplenial contributions to human spatial navigation

By Russell A. Epstein. Trends in Cognitive Sciences, 2008

943 citations recorded by the source corpus.

Spatial navigation is a core cognitive ability in humans and animals. Neuroimaging studies have identified two functionally-defined brain regions that activate during navigational tasks and also during passive viewing of navigationally-relevant stimuli such as environmental scenes: the parahippocampal place area (PPA) and the retrosplenial complex (RSC). Recent findings indicate that the PPA and RSC play distinct and complementary roles in spatial navigation, with the PPA more concerned with representation of the local visual scene and RSC more concerned with situating the scene within the broader spatial environment. These findings are a first step towards understanding the separate components of the cortical network that mediates spatial navigation in humans.

Subfields: Automotive Engineering, Cognitive Neuroscience, Developmental and Educational Psychology

View Paper: https://www.semanticscholar.org/paper/5d1181aeaa303b0267cc0971fc0183f47aba0792

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Automotive Engineering

1. Paul Graham
2. John D. E. Gabrieli
3. Dwight J. Kravitz
4. Matthias L. Schroeter
5. Chris L. Baker
6. David E. Osher
7. Timo Stein
8. Rebecca Saxe

In Cognitive Neuroscience

1. Rebecca Saxe
2. Chris L. Baker
3. John D. E. Gabrieli
4. Kadharbatcha S. Saleem
5. Mortimer Mishkin
6. Paul Graham
7. Dwight J. Kravitz
8. Matthias L. Schroeter

In Developmental and Educational Psychology

1. Rebecca Saxe
2. Chris L. Baker
3. John D. E. Gabrieli
4. Paul Graham
5. Dwight J. Kravitz
6. Matthias L. Schroeter
7. David E. Osher
8. Timo Stein

Citations in the corpus

• A new neural framework for visuospatial processing (2011, background): “. overlaps both the RSC and some portions of the PCC) has been identified and labelled the retrosplenial complex 131 .”
• Similarity judgments and cortical visual responses reflect different properties of object and scene categories in naturalistic images (2018, background): “…correlation emerged in areas corresponding to scene-selective regions PPA and OPA (Figure 7), as well as a medial parietal region that seems to correspond to a third scene-selective region (medial place area, MPA, also referred to as retrosplenial complex, RSC (Epstein, 2008; Silson et al., 2016b).”
• Neural Correlates of Alzheimer's Disease and Mild Cognitive Impairment: A Systematic and Quantitative Meta-Analysis involving 1,351 Patients (2009, positive): “Additionally, the hippocampus/parahippocampal cortex have been discussed in the context of spatial processing (Bird and Burgess, 2008; Epstein 2008).”
• What can we learn from studies of insect navigation (2012, background): “This region is involved in scene recognition, based on wide-field visual input, and treats scenes in a unified way, independently of the component elements (Epstein 2008).”
• Impact of Mindfulness-Based Stress Reduction Training on Intrinsic Brain Connectivity (2011, background): “The retrosplenial cortex is activated by scene viewing and imagery and is involved in placing a scene within a broader spatial environment by integrating egocentric spatial information into an allocentric environmental representation (Burgess, 2008; Epstein, 2008; O'Craven and Kanwisher, 2000).”
• The neuroscience of learning: beyond the Hebbian synapse. (2013, result): “Similar conclusions may be drawn from fMRI results in humans (Epstein 2008, 2011; MacEvoy & Epstein 2011; Morgan et al. 2010), but space does not permit a review.”
• Anatomical connectivity patterns predict face-selectivity in the fusiform gyrus (2011, positive): “Scene-selective voxels, by contrast, were best predicted by their connectivity to key brain areas involved in scene recognition, such as the isthmuscingulate (containing the retrosplenial cortex) and the parahippocampal corte”