New microRNAs from mouse and human.

By M. Lagos‐Quintana, R. Rauhut, Jutta Meyer, Arndt Borkhardt, Thomas Tuschl. RNA: A publication of the RNA Society, 2003

926 citations recorded by the source corpus.

Subfields: Cancer Research, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/5cccea5a33b169f104b2b04adf39afebfa2f0b25

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Citations in the corpus

Small non-coding RNAs in animal development (2008, background): “miR-124 is expressed specifically and abundantly in the mouse brain and in P19 pluripotent cells on their differentiation to neuron-like cell”
Detection and characterization of placental microRNAs in maternal plasma. (2008, neutral): “miR-16isubiquitousinalmostallsomatictissues( 26 ),”
A pattern-based method for the identification of MicroRNA binding sites and their corresponding heteroduplexes. (2006, background): “Early studies suggested only a limited role for RNAi but the subsequent discovery of many endogenously encoded microRNAs (Lagos-Quintana et al., 2001, 2003; Lee and Ambros, 2001) pointed toward the possibility of this being a more general control mechanism (Hobert, 2004).”
The Role of MicroRNAs in Human Diseases (2010, background): “The fact that many micro RNAs’ sequences are conserved among distantly related organisms indicates that miRNAs are involved in basic cellular processes ((40)).”
The Microprocessor complex mediates the genesis of microRNAs (2004, background): “Because these miRNAs have the same orientation as pre-mRNAs, it is likely that they are not transcribed from their own promoters but are processed from the intron”
Computational identification of Drosophila microRNA genes (2003, neutral): “identified by the direct cloning method [30].”
Human embryonic stem cells express a unique set of microRNAs. (2004, background): “The expression of miRNAs is often regulated in tissuespecific and developmental stage-specific manners (Aravin et al., 2003; Krichevsky et al., 2003; Lagos-Quintana et al., 2002; Pasquinelli et al., 2000; Sempere et al., 2003), although the regulatory mechanism is still largely unknown.”
Microarray analysis of microRNA expression in the developing mammalian brain (2004, neutral): “elegans, plants, Drosophila melanogaster and mammals [6-18].”
Prediction and validation of microRNAs and their targets (2005, neutral): “Initially, most microRNAs were discovered by massive cloning and sequencing eﬀorts [10–14], with informatics playing a limited role of verifying that the cloned sequences are part of a hairpin structure, typical of microRNA precursors [15].”