Glutamatergic synapses on oligodendrocyte precursor cells in the hippocampus

By D. Bergles, J. Roberts, Péter Somogyi, C. Jahr. Nature, 2000

1,018 citations recorded by the source corpus.

Subfields: Cellular and Molecular Neuroscience, Developmental Neuroscience, Neurology

View Paper: https://www.semanticscholar.org/paper/5bbc233239c918ee63ddd3feec1beff4075665de

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Cellular and Molecular Neuroscience

1. R. Malenka
2. C. Eroglu
3. B. Barres
4. Andrea Volterra
5. K. Nave
6. F. Kirchhoff
7. Philip Haydon
8. Richard L. Huganir

In Developmental Neuroscience

1. K. Nave
2. Philip Haydon
3. Andrea Volterra
4. C. Eroglu
5. R. Fields
6. M. Simons
7. R. Malenka
8. J. Meldolesi

In Neurology

1. C. Eroglu
2. B. Barres
3. Philip Haydon
4. F. Kirchhoff
5. R. Fields
6. M. Simons
7. Richard L. Huganir
8. K. Nave

Citations in the corpus

• Astrocytes, from brain glue to communication elements: the revolution continues (2005, background): “, NG2-positive cells receive direct synaptic inputs from neuronal fibre”
• Regulation of synaptic connectivity by glia (2010, background): “Fast synaptic transmission occurs between OPCs and axons, both in the hippocampus and the cerebellu”
• Neuronal Activity Promotes Glioma Growth through Neuroligin-3 Secretion (2015, positive): “It is possible that NLGN3 is secreted directly from active neurons or from OPCs, which act as post-synaptic cells in axoglial synapses (Bergles et al., 2010; Bergles et al., 2000) and express the highest level of Nlgn3 mRNA of any neural cell type (Zhang et al.”
• Polydendrocytes (NG2 cells): multifunctional cells with lineage plasticity (2009, methodology): “The physiological properties of polydendrocytes in a slice were first determined using post-recording immunocytochemistry to identify the recorded cell”
• Glutamate as a neurotransmitter in the healthy brain (2014, background): “Most, if not all, cells in the nervous system express at least one type of glutamate receptor (Steinhauser and Gallo 1996; Vernadakis 1996; Forsythe and Barnes-Davies 1997; Wenthold and Roche 1998; Petralia et al. 1999; Conti et al. 1999; Shelton and McCarthy 1999; Bergles et al. 2000).”
• White matter in learning, cognition and psychiatric disorders. (2008, positive): “Clusters of synaptic vesicles are seen by electron microscopy accumulating at some nodes of Ranvier [92], and functional synapses have been detected between axons and oligodendrocyte progenitor cells [ 93 ].”
• ATP released by astrocytes mediates glutamatergic activity-dependent heterosynaptic suppression. (2003, background): “…(10–20 M ; see also Lüscher et al., campal slices in response to perfusion of glutamate that mimics high-frequency neuronal activity, and the1998; Bergles et al., 2000), and absence of action poten- tials in response to membrane depolarizations (Figures ectonucleotidase inhibitor DPM (10 M)…”
• Myelination and support of axonal integrity by glia (2010, background): “, much recent work has been devoted to the role of AMPA (α-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid) and NMDA ( N -methyl- D -aspartate) type glutamate receptors on NG2 cells and myelinating oligodendrocyte”