Asthma. From bronchoconstriction to airways inflammation and remodeling.
By J. Bousquet, P. Jeffery, W. Busse, Malcolm W Johnson, A. Vignola. American Journal of Respiratory and Critical Care Medicine, 2000
1,898 citations recorded by the source corpus.
Subfields: Physiology, Pulmonary and Respiratory Medicine
View Paper: https://www.semanticscholar.org/paper/5a9138416d02404b88f88f0b47dc2f1650ae72c1
How researchers see this paper
The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.
In Physiology
In Pulmonary and Respiratory Medicine
Citations in the corpus
- Eosinophils: Biological Properties and Role in Health and Disease (2008, background): “…repair processes following repeated airway injury and involves an increase in airway smooth muscle mass, deposition of collagen and other c 2008 Blackwell Publishing Ltd, Clinical and Experimental Allergy, 38 : 709–750 matrix proteins, and new blood vessel formation (Bousquet et al. 1990).”
- Identification of Circulating Fibrocytes as Precursors of Bronchial Myofibroblasts in Asthma1 (2003, background): “The remodeling process has become an important target for therapeutic intervention (3, 5) because it may contribute to the chronic sequelae of asthma (6, 7), leading to permanently impaired pulmonary function and work disability (8).”
- The Airway Epithelium: Soldier in the Fight against Respiratory Viruses (2011, background): “Epithelial damage not only is characterized by modifications in morphology, such as loss of ciliated cells (29), but also is associated with perturbations in airway homeostasis, such as decreased production of smooth muscle relaxing factors (e.”
- Anti-IL-5 treatment reduces deposition of ECM proteins in the bronchial subepithelial basement membrane of mild atopic asthmatics. (2003, background): “The Journal of Clinical Investigation | October 2003 | Volume 112 | Number 7 1029 Introduction Allergic asthma is characterized by eosinophilic airway inflammation and structural changes in the airway wall termed remodeling (1).”
- Role of the CXCL8-CXCR1/2 Axis in Cancer and Inflammatory Diseases (2017, neutral): “Asthma is characterized by episodes of reversible airflow obstruction, bronchial constriction, and lung inflammation induced by allergens [164].”
- Direct effects of interleukin-13 on epithelial cells cause airway hyperreactivity and mucus overproduction in asthma (2002, background): “STAT6 is a critical signaling molecule activated by IL-13 receptor ligation and is essential for the development of allergen-induced experimental asthm”