Oxidative Stress and Cardiovascular Injury: Part I: Basic Mechanisms and In Vivo Monitoring of ROS

By K. Griendling, G. FitzGerald. Circulation, 2003

954 citations recorded by the source corpus.

Subfields: Biochemistry, Immunology, Physiology

View Paper: https://www.semanticscholar.org/paper/5a0d1d991d8263edcd8a48d4fc5aa533bb9e3741

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Biochemistry

1. F. Giordano
2. A. Tedgui
3. E. Schiffrin
4. Z. Mallat
5. R. Goldberg

In Immunology

1. F. Giordano
2. A. Tedgui
3. E. Schiffrin
4. Z. Mallat
5. R. Goldberg
6. R. Medzhitov

In Physiology

1. F. Giordano
2. A. Tedgui
3. E. Schiffrin
4. Z. Mallat
5. R. Goldberg

Citations in the corpus

• Vascular Inflammation and Oxidative Stress: Major Triggers for Cardiovascular Disease (2019, background): “In the intervening years, there has been recognition that the majority of cardiovascular diseases can be characterized as having an imbalance between the formation of ROS and ROS-degrading antioxidant systems [67, 97].”
• Cytokines in atherosclerosis: pathogenic and regulatory pathways. (2006, positive): “laminar and oscillatory shear stress) (252).”
• Oxygen, oxidative stress, hypoxia, and heart failure. (2005, background): “They are involved in a variety of cellular signaling pathways (28), acting in some instances as second messengers downstream of specific ligands, including TGF-β1, PDGF, ATII, FGF-2, endothelin, and others (14, 15, 29, 30).”
• Endothelial dysfunction. (2004, background): “Peroxynitrite is an important mediator of oxidation of LDL, emphasizing its proatherogenic role (28).”
• Cytokine and cytokine-like inflammation markers, endothelial dysfunction, and imbalanced coagulation in development of diabetes and its complications. (2009, background): “The underlying factors that stimulate expression of these genes include reactive oxygen species (ROS), oxidized lipids, reduced nitric oxide (NO), increased angiotensin II, free fatty acids (FFA) and advanced glycation end products (AGEs) (6, 7).”
• Biological markers of oxidative stress: Applications to cardiovascular research and practice (2013, background): “The short half-life of these species makes them excellent signalling molecules but confounds their measurement in the circulation of complex biological systems by standard approaches such as spin-trapping [7].”