Respiratory active mitochondrial supercomplexes.

By R. Acín-Pérez, P. Fernández-Silva, M. Peleato, A. Pérez-Martos, Jose Antonio Enríquez. Molecules and Cells, 2008

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Mitochondrial Cristae Shape Determines Respiratory Chain Supercomplexes Assembly and Respiratory Efficiency (2013, methodology): “Four days after Cremediated Opa1 ablation, mtDNA copy number (Figure 4F) and translation (Figures 4G and 4H) were unaffected, allowing us to specifically address the role of OPA1 and cristae shape in RCS assembly using an assay based on the incorporation of radiolabeled mtDNA-encoded proteins into R”
Mitochondrial Cristae: Where Beauty Meets Functionality. (2016, background): “According to the latest model, known as the ‘plasticity model’, OXPHOS complexes are present as both single complexes and supercomplexes (SCs) of different composition and stoichiometry [96].”
The Randle cycle revisited: a new head for an old hat. (2009, background): “The formal demonstration of the actual working of these complexes is lacking, although some experimental evidence has been presented for the presence of various supramolecular complexes and for substrate channeling (6, 66, 175).”
Mitochondrial genome acquisition restores respiratory function and tumorigenic potential of cancer cells without mitochondrial DNA. (2015, background): “RCs form supercomplexes (SCs), such as the respirasome (Schägger and Pfeiffer, 2010; Acin-Perez et al., 2008; Althoff et al., 2011) that transfers electrons from CI to CIV via CIII (Lapuente-Brun et al.”