Neuregulins: functions, forms, and signaling strategies.

By D. Falls. Experimental Cell Research, 2003

1,099 citations recorded by the source corpus.

Subfields: Immunology and Allergy, Oncology, Radiology, Nuclear Medicine and Imaging

View Paper: https://www.semanticscholar.org/paper/5832342051881e0b48abca315e5a9f9af30a3949

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Immunology and Allergy

1. J. Coyle
2. B. Trapp
3. K. Nave
4. C. Blobel

In Oncology

1. C. Blobel
2. D. Leahy
3. M. Sliwkowski
4. M. Lemmon
5. J. Coyle
6. B. Trapp
7. K. Nave
8. R. Roskoski

In Radiology, Nuclear Medicine and Imaging

1. C. Blobel
2. M. Sliwkowski
3. J. Coyle
4. B. Trapp
5. K. Nave
6. N. Hynes
7. M. Lacouture

Citations in the corpus

• Essential Role for ADAM19 in Cardiovascular Morphogenesis (2004, background): “It remains to be determined whether ADAM19 has a role in processing other neuregulin isoforms (11) in cells and tissues where both proteins are coexpressed, such as in the endocardium overlying the endocardial cushion and a limited portion of the outflow tract of the developing heart at E10.”
• Circuit-based framework for understanding neurotransmitter and risk gene interactions in schizophrenia. (2008, background): “Mice with a null mutation of its gene express lower levels of NR1 [151], and have altered tyrosine phosphorylation of the channel [152].”
• Axon-glial signaling and the glial support of axon function. (2008, background): “…proteins share an epidermal growth factor–like signaling domain that is necessary and sufficient for the activation of ErbB receptor tyrosine kinases, which are expressed by oligodendrocytes and Schwann cells (for details, see Adlkofer & Lai 2000, Falls 2003, Esper et al. 2006, Nave & Salzer 2006).”
• Essential roles of Meltrin β (ADAM19) in heart development (2004, background): “The biological effects of Neuregulin are mediated by tyrosine kinase receptors belonging to the ErbB family, which consists of epidermal growth factor receptor (EGFR/ErbB1), ErbB2, ErbB3, and ErbB4 (reviewed by Buonanno and Fischbach, 2001; Falls 2003).”
• Glutamate and Schizophrenia: Beyond the Dopamine Hypothesis (2006, background): “, 1998), Neuregulin (Falls, 2003), Regulator of G-protein Signaling 4 (RGS4; Williams et al.”
• An open-and-shut case? Recent insights into the activation of EGF/ErbB receptors. (2003, background): “ErbB2 has no known direct activating ligand (Citri et al., 2003), while ErbB3 and/or ErbB4 function as receptors for the four known neuregulins (NRGs) (Falls, 2003).”