Glutamate and Schizophrenia: Beyond the Dopamine Hypothesis

By J. Coyle. Cellular and molecular neurobiology, 2006

977 citations recorded by the source corpus.

Subfields: Cellular and Molecular Neuroscience, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/ea12858360fa1fef94cdd48e1c2238340458d4ba

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Cellular and Molecular Neuroscience

1. E. T. Rolls
2. R. McCutcheon
3. Gustavo Deco
4. J. Stone
5. Georg Winterer
6. P. Penzes
7. Marco Loh
8. M. Cahill

In Molecular Biology

1. E. T. Rolls
2. Gustavo Deco
3. Georg Winterer
4. Oliver D. Howes
5. R. Kesner
6. Fabian Grabenhorst

Citations in the corpus

• Glutamate and dopamine in schizophrenia: an update for the 21st century (2015, background): “…interactions, and thus it may be difficult to determine which is primary, with different authorities on the subject suggesting that both glutamate and dopamine drive abnormalities in the other system (Coyle, 2006; Harrison and Weinberger, 2005; Olney and Farber, 1995; Stone et al., 2007).”
• Computational models of schizophrenia and dopamine modulation in the prefrontal cortex (2008, background): “Any factor that reduces the currents through the NMDA ( N -methyl- D -aspartate) receptors (NMDARs) on the pyramidal cells, as seems to occur in patients with schizophreni”
• Dendritic spine pathology in neuropsychiatric disorders (2011, background): “A loss of scaffolding proteins in spines could alter glutamatergic receptor signaling, disruption of which is theorized to contribute to the etiology of schizophreni”