Oxytocin attenuates amygdala responses to emotional faces regardless of valence.

By G. Domes, M. Heinrichs, Jan Gläscher, Christian Büchel, D. Braus, Sabine C. Herpertz. Biological Psychiatry, 2007

799 citations recorded by the source corpus.

Subfields: Behavioral Neuroscience, Experimental and Cognitive Psychology, Social Psychology

View Paper: https://www.semanticscholar.org/paper/5727ac51ad6fb67d81cc3ef2c04440c179bd53ab

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Citations in the corpus

Oxytocin, vasopressin, and human social behavior. (2009, background): “In addition, exploratory whole brain analysis revealed modulatory effects in prefrontal and temporal areas, as well as in the brainstem [43].”
The Social Salience Hypothesis of Oxytocin. (2016, positive): “For example, Kumsta and Heinrichs (46) list in their review studies showing that inOT attenuates neuroendocrine stress reactivity (48), decreases amygdala activation in response to threatening stimuli (49), as well as an association between the OT receptor gene rs53576 and dispositional empathy and ”
The Challenge of Translation in Social Neuroscience: A Review of Oxytocin, Vasopressin, and Affiliative Behavior (2010, neutral): “In fact, OT appears to reduce the amygdala response to emotional expression irrespective of valence (Domes et al., 2007a).”
Oxytocin and vasopressin in the human brain: social neuropeptides for translational medicine (2011, positive): “Additional brain imaging studies using different stimuli and experimental approaches replicated the dampening effect of OXT on amygdala activity in male”
Oxytocin shapes the neural circuitry of trust and trust adaptation in humans. (2008, positive): “Moreover, both human neuroimaging (Domes et al., 2007a; Kirsch et al., 2005) and animal studies (Huber et al., 2005) have shown that the neuropeptide OT decreases fear responses bymodulating activation in the amygdala and brainstem effector sites.”
Oxytocin Enhances Amygdala-Dependent, Socially Reinforced Learning and Emotional Empathy in Humans (2010, background): “In humans, OT enhances inference of emotional states (Domes et al., 2007a) as well as trust in (Kosfeld et al., 2005; Baumgartner et al., 2008) and generosity toward (Zak et al., 2007) others, suggesting that OT has empathogenic properties and could influence behavior in the context of social…”
sCARF : a brain-based model for collaborating with and influencing others (2009, background): “…with the other person. oxytocin is a hormone produced naturally in the brain, and higher levels of this substance are associated with greater affiliative behavior (Domes et al, 2007). studies have shown far greater collaboration when people are given a shot of oxytocin, through a nasal spray.”
Oxytocin: the Great Facilitator of Life (2009, neutral): “Intranasal Oxt also improves the ability to infer the mental state of others from social cues in the eye region (Domes et al., 2007b).”
Psychobiological Mechanisms Underlying the Social Buffering of the HPA Axis: A Review of Animal Models and Human Studies across Development (2013, background): “, & Mori, Y. (2004). Partner’s stress status influences social buffering effects in rats.”
The role of oxytocin in social bonding, stress regulation and mental health: an update on the moderating effects of context and interindividual differences. (2013, background): “In support of these findings, neuroimaging studies have shown that intranasal oxytocin administration diminished amygdala activity (e.g. Domes et al., 2007) and decreased functional coupling between the amygdala and brainstem (Kirsch et al., 2005) in healthy males in response to negative emotional…”
The neuroscience of social decision-making. (2011, positive): “Several studies have now demonstrated that the neuropeptide oxytocin (OT) reduces amygdala activity in male subjects (Baumgartner et al. 2008, Domes et al. 2007, Kirsch et al. 2005, Petrovic et al. 2008, Singer et al. 2008) although not in women (Domes et al. 2010), and others have shown that OT…”
Oxytocin receptor genetic variation relates to empathy and stress reactivity in humans (2009, background): “Furthermore, intranasal oxytocin reduces amygdala activation and cortisol increases to emotional stimuli (20, 37).”