CRACM1 Is a Plasma Membrane Protein Essential for Store-Operated Ca2+ Entry

By M. Vig, C. Peinelt, Andreas Beck, D. Koomoa, D. Rabah, M. Koblan-Huberson, S. Kraft, Helen Turner, A. Fleig, R. Penner and 1 more. Science, 2006

1,367 citations recorded by the source corpus.

Subfields: Molecular Biology, Plant Science, Sensory Systems

View Paper: https://www.semanticscholar.org/paper/55804492200af0941bf82ba11b53f9076f894eb5

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Molecular Biology

1. Stephen H. Bryant
2. R. Lewis
3. P. Hogan
4. M. Prakriya
5. Benjamin A. Shoemaker
6. Siqian He
7. Jiyao Wang
8. Jian Zhang

In Plant Science

1. R. Lewis
2. T. Balla
3. M. Prakriya

In Sensory Systems

1. R. Lewis
2. M. Prakriya
3. S. Feske
4. Heike Wulff
5. E. Skolnik
6. Anjana Rao
7. P. Hogan
8. Jie Zheng

Citations in the corpus

• Phosphoinositides: tiny lipids with giant impact on cell regulation. (2013, background): “This was followed within a year by the discovery of the Orai1 protein as the channel component of ICRAC, the highly Ca(2) -selective current representing the major form of SOCE (435, 1635, 1802).”
• STIM proteins: dynamic calcium signal transducers (2012, background): “(Ins(1,4,5) P 3 ) and diacylglycerol (DAG) are generated”
• SOAR and the polybasic STIM1 domains gate and regulate the Orai channels (2009, background): “(1) Orail1+ SOAR (2) Orail1 + SOARLQ/AA (3) Orai1 + STIM1 (4) Orail1 + STIM1LQ/AA”
• PubChem BioAssay: 2014 update (2013, background): “BioAssay datasets added during the past 2 years include (i) small molecule data from screening centers of the NIH Molecular Libraries and Imaging Program [Molecular Library Program (MLP)] (http://commonfund.nih.gov/ molecularlibraries/), ICCB-Longwood/NSRB Screen Facility at the Harvard Medical Scho”
• Dual functions for the endoplasmic reticulum calcium sensors STIM1 and STIM2 in T cell activation and tolerance (2008, background): “The drosophila protein Orai (encoded by olf186-F ), identified as an essential regulator of store-operated Ca 2+ influx by a series of genome-wide drosophila RNA-mediated interference screen”
• FlyMine: an integrated database for Drosophila and Anopheles genomics (2007, background): “melanogaster WormBase Drosophila RNAi screening center [75-78] [79-85]”
• Store-Operated Calcium Channels. (2015, positive): “At the same time, the Kinet and Cahalan groups (398, 446), conducting their own screens of the S2 RNAi library for suppression of SOCE, identified the same olf186-F gene in S2 cells, and Vig et al.”