An Apolipoprotein Influencing Triglycerides in Humans and Mice Revealed by Comparative Sequencing
By Len A. Pennacchio, Michael Olivier, J. Hubacek, Jonathan C. Cohen, D. Cox, J. Fruchart, Ronald M. Krauss, Edward M. Rubin. Science, 2001
964 citations recorded by the source corpus.
Subfields: Endocrinology, Diabetes and Metabolism, Molecular Biology, Surgery
View Paper: https://www.semanticscholar.org/paper/555aaa3b3d9648df272e8a820db263587a457d5b
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In Endocrinology, Diabetes and Metabolism
In Molecular Biology
- Gregory M. Cooper
- Bart Staels
- Eric A. Stone
- Serafim Batzoglou
- Arend Sidow
- G. Asimenos
- Eric D. Green
- Kazutaka Katoh
In Surgery
Citations in the corpus
- Molecular mechanism of PPARα action and its impact on lipid metabolism, inflammation and fibrosis in non-alcoholic fatty liver disease. (2015, background): “Studies using human LPL transgenic/ Apo-AV-deficient mice and human APO-AV transgenic/Lpldeficient mice support the hypothesis that APO-AV reduces TG levels by trafficking VLDL and chylomicrons to proteoglycanbound LPL for lipolysis [86,87].”
- Brown adipose tissue activity controls triglyceride clearance (2011, background): “To gain further mechanistic insight into BAT-mediated TRL processing, we studied turnover and organ uptake of radiolabeled TRLs in transgenic mouse models that have defective function of proteins key for lipolysis (apolipoprotein AV (apoAV)”
- Metabolic origins and clinical significance of LDL heterogeneity DOI 10.1194/jlr.R200004-JLR200 (2002, background): “A subset of 501 subjects in this population is described in reference (211).”
- Distribution and intensity of constraint in mammalian genomic sequence. (2005, background): “Considering such estimates, as well as recent studies that successfully leveraged sequence conservation to identify regions of functional importance in mammals (Pennacchio et al. 2001; Göttgens et al. 2002; Boffelli et al. 2003; Ghanem et al. 2003; Brugger et al. 2004), it is clear that comparative ”
- Systematic discovery of regulatory motifs in human promoters and 3′ UTRs by comparison of several mammals (2005, neutral): “42 miR-26b, miR-26a, new(4) 10 CGCAAAAA 0.”