GABAergic signaling to newborn neurons in dentate gyrus.

By Linda Overstreet Wadiche, Daniel A. Bromberg, AeSoon Bensen, G. Westbrook. 2005

273 citations recorded by the source corpus.

Subfields: Cellular and Molecular Neuroscience, Developmental Neuroscience, Neurology

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Citations in the corpus

New neurons and new memories: how does adult hippocampal neurogenesis affect learning and memory? (2010, background): “However, these immature DGCs receive synaptic GABAergic input, presumably from local interneurons, and the resulting responses have slow rising and decay kinetic”
Distinct Determinants of Sparse Activation during Granule Cell Maturation (2013, background): “Consistent with this idea, developing GCs receive GABAergic synapses from interneurons like Ivy/ Neurogliaform cells that generate slow dendritic conductances before innervation by perisomatic-targeting basket cells that generate IPSCs with rapid kinetics (Espósito et al., 2005; Overstreet Wadiche ”
Delayed Development of Adult-Generated Granule Cells in Dentate Gyrus (2006, background): “Although they lack glutamatergic synaptic input, newborn granule cells have depolarized GABAergic responses and GABAergic synaptic currents with slow decay phases in adults and neonates (Overstreet-Wadiche et al., 2005).”
Synaptic integration and plasticity of new neurons in the adult hippocampus (2008, background): “…tonic activation by ambient GABA, to dendritic GABAergic synaptic inputs, followed by dendritic glutamatergic inputs and finally perisomatic GABAergic inputs (Esposito et al. 2005; Overstreet Wadiche et al. 2005, 2006; Tozuka et al. 2005; Wang et al. 2005; Ge et al. 2006; Karten et al. 2006).”
Seizure-Associated, Aberrant Neurogenesis in Adult Rats Characterized with Retrovirus-Mediated Cell Labeling (2007, background): “Why we and others (Parent et al., 1997; Scharfman et al., 2000; OverstreetWadiche et al., 2006; Shapiro and Ribak, 2006), in contrast to Jakubs et al. (2006), have found dramatic differences in the neuronal morphology of newborn granule cells remains unclear, but it might be explained by the seizure”
Adult neurogenesis and the plasticity of the dentate gyrus network (2011, background): “Similarly to what occurs during development, early inputs are exclusively GABAergic contacts distributed in the dendrites (Espósito et al., 2005; Overstreet Wadiche et al., 2005; Markwardt et al., 2009).”
Mechanisms and functional implications of adult neurogenesis. (2008, unknown): “Newborn neurons in the dentate gyrus go through several developmental stages with distinctive physiological and morphological properties (Figures 2 and 4) (Esposito et al., 2005; Ge et al., 2006; Overstreet Wadiche et al., 2005; Zhao et al., 2006).”
Dopaminergic Modulation of Cortical Inputs during Maturation of Adult-born Dentate Granule Cells (2011, background): “DGCs generated in the adult hippocampus receive synaptic inputs from the entorhinal cortex and local inhibitory interneurons (van Praag et al., 2002; Overstreet Wadiche et al., 2005; Laplagne et al., 2006) and form functional synapses with interneurons and CA3 pyramidal cells (Toni et al., 2008).”
Brain micro-ecologies: neural stem cell niches in the adult mammalian brain (2008, background): “As in the SVZ, GABA is excitatory for progenitors and newly generated neurons; however, it is released synaptically, probably by local inhibitory interneurons (Overstreet Wadiche et al. 2005; Tozuka et al. 2005; Wang et al. 2005; Ge et al. 2006).”
Neuronal Differentiation in the Adult Hippocampus Recapitulates Embryonic Development (2005, background): “During the early stages of maturation, neurons displayed a high Rinput and low Cm, properties that are typical of immature neurons in the developing and adult brain (Owens et al., 1996; Carleton et al., 2003; Zhang, 2004; Overstreet Wadiche et al., 2005; Ye et al., 2005).”
Visualization and genetic manipulation of adult neurogenesis using transgenic mice (2011, background): “high intracellular Cl concentration (Wadiche et al., 2005; Karten et al., 2006; Markwardt et al., 2009).”
Development of GABAergic inputs controls the contribution of maturing neurons to the adult hippocampal network (2012, unknown): “Admittedly, this is a simplified model, as GABA inputs likely precede glutamatergic inputs (6), but the developmental timeline of overall GABA inputs described here is comparable to the rapid increase of dendritic spines from approximately 3 wk to 6 wk (5).”
The role of adult hippocampal neurogenesis in brain health and disease (2018, background): “Giachino C, Barz M, Tchorz JS, Tome M, Gassmann M, Bischofberger J, et al. GABA suppresses neurogenesis in the adult hippocampus through GABAB receptors.”
Excitatory GABA Action Is Essential for Morphological Maturation of Cortical Neurons In Vivo (2007, background): “…in these regions of the adult brain in a manner similar to the development of neurons in the early developing brain, with the presence of excitatory GABA action before the glutamatergic input (Ming and Song, 2005; Overstreet et al., 2005; Song et al., 2005; Overstreet-Wadiche and Westbrook, 2006).”