Development of GABAergic inputs controls the contribution of maturing neurons to the adult hippocampal network

By Yan Li, James Bradley Aimone, Xiangmin Xu, Edward M. Callaway, Fred H. Gage. 2012

63 citations recorded by the source corpus.

Subfields: Cellular and Molecular Neuroscience, Cognitive Neuroscience, Neurology

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Citations in the corpus

Re-evaluating circuit mechanisms underlying pattern separation (2019, positive): “, 2016) receive reduced synaptic inhibition (Li et al., 2012; Marin-Burgin et al., 2012; Dieni et al., 2013).”
Modeling Hippocampal Neurogenesis Using Human Pluripotent Stem Cells (2014, background): “Finally, studies have also shown a transition in hippocampal granule neurons from a GABA-excitatory to a GABA-inhibitory state during early maturation as a result of changes in intracellular Cl concentration due to the upregulation of the KCC2 channel (Ganguly et al., 2001; Li et al., 2012).”
Molecular layer perforant path-associated cells contribute to feed-forward inhibition in the adult dentate gyrus (2013, methodology): “We pooled data from stimulation sites in three different hippocampal regions: ML, GCL, and hilus (H), and then calculated the means for all stimulation sites within each region (10).”
Adult Neurogenesis in the Hippocampus: From Stem Cells to Behavior. (2016, unknown): “…DG excitability; experiments in hippocampal slices suggest that immature adult-born neurons are poorly coupled to inhibitory neurons in the DG and hilus (Temprana et al., 2015) while being subject to feedback and feedforward inhibitory inputs themselves (Dieni et al., 2016; Li et al., 2012, 2013b).”
Distinct Determinants of Sparse Activation during Granule Cell Maturation (2013, background): “Comparing the amplitude of EPSCs in spiking GCs also showed that 4 week PTI GCs could spike in response to less excitatory drive (Mongiat et al., 2009; Li et al., 2012; Fig.”