Ascorbic acid: much more than just an antioxidant.

By O. Arrigoni, M. D. De Tullio. Biochimica et Biophysica Acta, 2002

933 citations recorded by the source corpus.

Subfields: Biochemistry, Materials Chemistry, Nutrition and Dietetics

View Paper: https://www.semanticscholar.org/paper/53bf819e01eeb1bf1ee218339bbb480fba59497f

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Materials Chemistry

1. J. M. May
2. Bo Zhao
3. Xiaoqing Jiang
4. Shaopeng Qi
5. F. Harrison
6. Heqing Tang

In Nutrition and Dietetics

1. J. M. May
2. R. Viola
3. F. Harrison
4. R. D. Hancock

Citations in the corpus

• Biosynthesis and Catabolism of L-Ascorbic Acid in Plants (2005, background): “A descrption of the physiological functions of AsA in plants is outside the scope of the present work and interested readers are directed to recently published reviews in this area ( Horemans et al. , 2000 ; Smirnoff, 2000 ; Arrigoni and De Tullio, 2002 ; Potters et al.”
• Vitamin C enhances the generation of mouse and human induced pluripotent stem cells. (2010, background): “We found that a combination of vitamin B1 (Vb1), reduced gluthatione (GSH monoethyl ester, GMEE), sodium selenite (Sel), and ascorbic acid (vitamin C, or Vc) ( Arrigoni and De Tullio, 2002 ) significantly accelerated the appearance of GFP+ cells in MEFs carrying a transgenic Oct4-GFP”
• Vitamin C Function in the Brain: Vital Role of the Ascorbate Transporter (SVCT2) (2009, background): “Intracellular ascorbate concentrations in the low millimolar range (much higher than those in plasma) seem to be necessary to support its role as an antioxidant [17] and as a cofactor for dioxygenase enzymes [18,19].”
• The changing faces of glutathione, a cellular protagonist. (2003, background): “Due to its properties (presence in adequate amounts within the cells; capability to react with a variety of free radicals; suitability of regeneration) ascorbic acid can be viewed as the ‘perfect antioxidant’ for the cells of nearly all aerobic organisms [18].”
• Effects of dietary ascorbic acid on oxygen stress (hypoxia or hyperoxia), growth and tissue vitamin concentrations in juvenile rainbow trout (Oncorhynchus mykiss) (2004, background): “Second, hyperoxia through the generation of free radicals and other prooxidants may result in damage to lipids, proteins, and DNA (Arrigoni and DeTullio, 2002).”
• Redox homeostasis via gene families of ascorbate-glutathione pathway (2015, background): “AsA and GSH have been known to play important roles in organ developmental pro - cesses of plants ( Arrigoni and De Tullio , 2002 ) .”
• Determination of ascorbic acid, dopamine, and uric acid by a novel electrochemical sensor based on pristine graphene (2015, background): “The imbalance of their contents is likely to cause some diseases, such as cancer [11], Parkinson's disease [12], and cardiovascular disease [13].”