Gene expression patterns in human embryonic stem cells and human pluripotent germ cell tumors
By J. Sperger, Xin Chen, J. Draper, J. Antosiewicz, Chris H. Chon, S. Jones, J. Brooks, P. Andrews, Patrick O. Brown, James A. Thomson. Proceedings of the National Academy of Sciences of the United States of America, 2003
674 citations recorded by the source corpus.
Subfields: Molecular Biology
View Paper: https://www.semanticscholar.org/paper/53338d6408b857b2e174553b5ccd640a967d7dbf
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In Molecular Biology
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Citations in the corpus
- c-Myc controls the balance between hematopoietic stem cell self-renewal and differentiation. (2004, background): “Detachment from the niche induces stem cell differentiation and loss of self-renewal (Spradling et al. 2001; Song and Xie 2002; Song et al. 2002).”
- Transposable elements have rewired the core regulatory network of human embryonic stem cells (2010, background): “This gene, which was previously reported as one of the most highly expressed genes in human embryonic stem cell”
- The tumorigenicity of human embryonic and induced pluripotent stem cells (2011, background): “10 ), and remarkable similarities in their overall gene expression pattern”
- Hyperdynamic plasticity of chromatin proteins in pluripotent embryonic stem cells. (2006, background): “The transition from undifferentiated, pluripotent ES cells to differentiated or partially differentiated cells involves dramatic changes in genome expression profiles (Ahn et al., 2004; Kelly and Rizzino, 2000; Loring et al., 2001; Sperger et al., 2003).”
- Chromatin in pluripotent embryonic stem cells and differentiation (2006, methodology): “More in line with those observations, the position of at least some chromosomes might be variable, as human chromosome 12, which contains a genomic region that is enriched with ES-cell-specific gene”
- An embryonic stem cell–like gene expression signature in poorly differentiated aggressive human tumors (2008, methodology): “We first analyzed the enrichment patterns of the 13 gene sets in an expression profile dataset that included 5 human ES lines, 7 embryonic carcinoma (EC) lines and various other normal and tumorigenic cells and tissue”
- Embryonic stem cells: prospects for developmental biology and cell therapy. (2005, background): “(339) compared the expression profiles of hES cell lines with human germ cell tumor cell lines, tumor samples, somatic cell lines, and testicular tissue samples.”