Finding a way out: lymphocyte egress from lymphoid organs

By Susan R. Schwab, J. Cyster. Nature Immunology, 2007

640 citations recorded by the source corpus.

Subfields: Hematology, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/5200f307e4fbf7b0a8bf4fa932b2f89c3a9092f5

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In Hematology

1. Sarah Spiegel
2. D. Chaplin
3. S. Milstien

In Molecular Biology

1. Sarah Spiegel
2. S. Milstien
3. J. Chun
4. K. Alitalo
5. T. Tammela
6. K. Takabe
7. Rafi Ahmed
8. D. Chaplin

Citations in the corpus

• “Inside-Out” Signaling of Sphingosine-1-Phosphate: Therapeutic Targets (2008, background): “ing and actions (Schwab and Cyster, 2007) (Fig.”
• Orchestrating the orchestrators: chemokines in control of T cell traffic (2008, background): “Chemokines organize the migration of naive T cells to and in lymph nodes, whereas the lipid G protein–coupled receptor agonist sphingosine 1-phosphate (S1P) coordinates lymph node egres”
• THE ALLIANCE OF SPHINGOSINE-1-PHOSPHATE AND ITS RECEPTORS IN IMMUNITY (2008, background): “and in controlling their egress into blood and lymp”
• Lymphangiogenesis: Molecular mechanisms and future promise. (2010, background): “Lymphocytes express the G protein-coupled S1P receptor S1P1 (also known as EDG-1) and exit from the lymph nodes to the lymph following a gradient of S1P, likely produced by LECs (Ledgerwood et al., 2008; Schwab and Cyster, 2007).”
• Dynamic T cell migration program provides resident memory within intestinal epithelium (2010, background): “Memory IELs are resident FTY720 treatment causes an accumulation of recirculating lymphocytes within lymphoid tissue and a corresponding decrease within other tissues that contain recirculating lymphocytes (Schwab and Cyster, 2007).”
• Mechanism of Action of Oral Fingolimod (FTY720) in Multiple Sclerosis (2010, background): “The S1P levels in different tissues are maintained by the orchestrated activities of enzymes that regulate sphingolipid metabolism, including kinases, lyases, and phosphatases.(39,63) The essential role of expressed S1P1 on lymphocytes and their interaction with S1P in the control of lymphocyte reci”
• Overview of the Immune Response (2003, background): “In addition to chemokine signals that control leukocyte entry into and migration within secondary lymphoid tissues, it is now understood that specific signals, especially those provided by the lysophospholipid sphingosine-1-phosphate, regulate the egress of cells out of the lymphoid tissues and into”