Zinc requirements and the risks and benefits of zinc supplementation.

By W. Maret, H. Sandstead. Journal of Trace Elements in Medicine and Biology, 2006

1,107 citations recorded by the source corpus.

Subfields: Health, Toxicology and Mutagenesis, Hematology, Nutrition and Dietetics

View Paper: https://www.semanticscholar.org/paper/513e2dddef87f9a846dd597e5c4664d891f339d2

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Health, Toxicology and Mutagenesis

1. S. Jafari
2. S. Gharibzahedi
3. C. Brauner
4. A. Farrell
5. L. Rink
6. C. Wood
7. W. Maret
8. D. Weiss

In Hematology

1. S. Jafari
2. S. Gharibzahedi
3. L. Rink
4. C. Wood
5. C. Brauner
6. A. Farrell
7. W. Maret
8. R. Hurrell

In Nutrition and Dietetics

1. S. Jafari
2. S. Gharibzahedi
3. L. Rink
4. I. Wessels
5. M. Maywald
6. Roya Kelishadi
7. Rainer Schulin
8. R. Hurrell

Citations in the corpus

• The importance of minerals in human nutrition: Bioavailability, food fortification, processing effects and nanoencapsulation (2017, positive): “Undesirable dif fi culties including eye and skin lesions, hair loss, weight loss or impotence, delayed sexual maturation, diarrhea, taste abnormalities, and mental lethargy can be also occurred in more critical cases of Zn shortage (Maret & Sandstead, 2006).”
• Heavy Metals and Human Health: Mechanistic Insight into Toxicity and Counter Defense System of Antioxidants (2015, background): “treatment of Zn has been assocated wth the depletion of copper [217,245].”
• Zinc and its importance for human health: An integrative review (2013, background): “Numerous zinc supplementation trials have shown that a wide range of health benefits can be realized by increasing the intake of zinc where diets are inadequate in this micronutrient.[49,63] The results of these trials strongly argue for the development of programs to improve zinc status in high-ris”
• Zinc and Oxidative Stress: Current Mechanisms (2017, background): “These adverse effects include decreased expression of copper-dependent enzymes, such as superoxide dismutase and ceruloplasmin, which are important in antioxidant defense [44,45].”
• Homeostasis and toxicology of essential metals (2012, background): “In humans, the most sensitive known functions to be adversely affected by high dietary Zn include hematological parameters and these are generally believed to be related to inhibition of Fe and Cu uptake in the gut (Maret and Sandstead, 2006; Stefanidou et al., 2006).”
• Zinc as a Gatekeeper of Immune Function (2017, result): “As the origin of zinc for TLR-triggered zinc signals is largely protein and organelle-based, this is also in line with previous findings [94,98,212].”
• Familial Occurrence of KienbockÂ’s Disease (2011, background): “Scientists has not determined whether differences exist among forms of zinc in absorption, bioavailability, or tolerability [17].”
• Zinc biochemistry: from a single zinc enzyme to a key element of life. (2013, background): “This intricate balance at a relatively narrow and tightly controlled range of concentrations needs to be considered when the physiological significance of results from experiments performed with zinc are evaluated and in nutrition when supplementation with zinc is considered (97).”