Inorganic nitrate is a possible source for systemic generation of nitric oxide.

By J. Lundberg, M. Govoni. Free Radical Biology & Medicine, 2004

691 citations recorded by the source corpus.

Subfields: Biochemistry, Endocrine and Autonomic Systems, Physiology

View Paper: https://www.semanticscholar.org/paper/513a5c55275c54083e90055fa091fb029c75f9c1

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Biochemistry

1. E. Weitzberg
2. J. Lundberg
3. F. Larsen
4. B. Ekblom
5. Emmelie A Jansson
6. M. Govoni
7. N. Bryan
8. K. Sahlin

In Endocrine and Autonomic Systems

1. E. Weitzberg
2. F. Larsen
3. B. Ekblom
4. J. Lundberg
5. Emmelie A Jansson
6. M. Govoni

In Physiology

1. E. Weitzberg
2. J. Lundberg
3. F. Larsen
4. B. Ekblom
5. N. Bryan
6. Emmelie A Jansson
7. M. Govoni
8. K. Sahlin

Citations in the corpus

• The increase in plasma nitrite after a dietary nitrate load is markedly attenuated by an antibacterial mouthwash. (2008, methodology): “Contents lists available at ScienceDirect Nitric Oxide journal homepage: www.elsevier .com/ locate/yniox The increase in plasma nitrite after a dietary nitrate load is markedly attenuated by an antibacterial mouthwash Mirco Govoni, Emmelie Å. Jansson, Eddie Weitzberg, Jon O. Lundberg * Department of”
• The nitrate–nitrite–nitric oxide pathway in physiology and therapeutics (2008, background): “The bioactivation of nitrate from dietary or endogenous sources requires its initial reduction to nitrite, and because mammals lack specific and effective nitrate reductase enzymes, this conversion is mainly carried out by commensal bacteria in the gastrointestinal tract and on body surface”
• Dietary nitrate supplementation reduces the O2 cost of low-intensity exercise and enhances tolerance to high-intensity exercise in humans. (2009, background): “The bacterially derived NO2 can increase circulating plasma NO2 and undergo reduction to yield NO in hypoxia or acidosis (21, 46).”
• Food sources of nitrates and nitrites: the physiologic context for potential health benefits. (2009, background): “Typical plasma concentrations, half-lives, and sources of nitrate, nitrite, and nitric oxide are shown in Table 1 (45, 51).”
• Dietary inorganic nitrate improves mitochondrial efficiency in humans. (2011, methodology): “Analysis of Nitrate and Nitrite Nitrate and nitrite were analyzed by chemiluminescence after reductive cleavage and determination of the NO released into the gas phase as previously described (Lundberg and Govoni, 2004).”
• Dietary nitrate supplementation enhances muscle contractile efficiency during knee-extensor exercise in humans. (2010, background): “Swallowed NO2 can be converted to NO in the stomach (9, 55) but some is absorbed to increase the circulating plasma [NO2 ] (19, 54).”
• Effects of dietary nitrate on oxygen cost during exercise (2007, methodology): “The plasma was separated and kept at )80 C until it was analysed for its nitrate and nitrite concentrations by a chemiluminescence assay as described previously (Lundberg & Govoni 2004).”