Transcriptional repression by AtMYB4 controls production of UV‐protecting sunscreens in Arabidopsis

By Hailing Jin, E. Cominelli, Paul Bailey, A. Parr, Frank Mehrtens, Jonathon Jones, C. Tonelli, Bernd Weisshaar, Cathie Martin. EMBO Journal, 2000

912 citations recorded by the source corpus.

Subfields: Molecular Biology, Plant Science

View Paper: https://www.semanticscholar.org/paper/4fb4fb69863797d14d7239f92989f524893ea575

How researchers see this paper

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In Molecular Biology

1. T. Umezawa
2. Z. Ye
3. R. Zhong
4. Erich Grotewold
5. Kazuo Shinozaki
6. M. Ohme-Takagi
7. Jianli Zhou
8. Chanhui Lee

In Plant Science

1. T. Umezawa
2. Kazuo Shinozaki
3. M. Ohme-Takagi
4. I. Somssich
5. Z. Ye
6. R. Zhong
7. Erich Grotewold
8. Jianli Zhou

Citations in the corpus

• An R2R3 MYB transcription factor associated with regulation of the anthocyanin biosynthetic pathway in Rosaceae (2010, background): “Several repressors of the phenylpropanoid pathway, and perhaps anthocyanins specifically, are also MYB TFs, including an R2R3 MYB repressor from strawberry FaMYB1 [19], Arabidopsis AtMYB6, 4, and 3 [20], Antirrhinum AmMYB308 [21], and a one repeat MYB in Arabidopsis, AtMYBL2 [22,23].”
• Repression Domains of Class II ERF Transcriptional Repressors Share an Essential Motif for Active Repression (2001, background): “AtMYB4 is a transcriptional repressor, and its repression domain has been mapped to the C-terminal region (Jin et al., 2000).”
• Enhancement of oxidative and drought tolerance in Arabidopsis by overaccumulation of antioxidant flavonoids (2013, background): “Overaccumulation of hydroxycinnamate ester confers UV-B tolerance in Arabidopsis (Jin et al., 2000).”
• Stamen Structure and Function (2004, background): “Because otherMYBs are known to regulate the phenylpropanoid pathway (e.g., AtMYBb4 [Jin et al., 2000]), the role of MYB26may be to activate this pathway in endothecial cells to provide lignin residues for wall thickening.”
• Molecular characterization of EgMYB1, a putative transcriptional repressor of the lignin biosynthetic pathway (2007, background): “It is also worth noting that some proteins of the subgroup 4 have been shown to regulate phenylpropanoid pathway genes [11,12,14,27,28].”
• Comprehensive identification of Arabidopsis thaliana MYB transcription factors interacting with R/B-like BHLH proteins. (2004, methodology): “subgroup 4, characterized by a C-terminal amino acid motif predicted to be involved in transcriptional repression (Aharoni et al., 2001; Jin et al., 2000; Stracke et al., 2001).”
• Multiple cis-regulatory elements regulate distinct and complex patterns of developmental and wound-induced expression of Arabidopsis thaliana 4CL gene family members (2006, background): “AtMYB32 (Preston et al. 2004) and AtMYB4 are shown to be involved in the wounding response and AtMYB4 transcription levels decreased 46 h postwounding (Jin et al. 2000).”
• The MYB Transcription Factor Superfamily of Arabidopsis: Expression Analysis and Phylogenetic Comparison with the Rice MYB Family (2005, background): “…et al., 1987; Grotewold et al., 1994; Bender and Fink, 1998; Hoeren et al., 1998; Mol et al., 1998, Tamagnone et al., 1998; Borevitz et al., 2000; Jin et al., 2000; Nesi et al., 2001; Baudry et al., 2004), the control of cell morphogenesis (Oppenheimer et al., 1991, Noda et al., 1994; Glover et…”
• Expression Profile Matrix of Arabidopsis Transcription Factor Genes Suggests Their Putative Functions in Response to Environmental Stresses (2002, background): “In another example in which plant response to UV irradiation was studied, knockout mutants for the Arabidopsis AtMyb4 gene were found to produce a higher level of UV light–protective compounds, such as sinapate esters, and to be more tolerant to UV-B light, whereas transgenic plants overexpressing A”
• Lignin biosynthesis. (2003, background): “CAD, cinnamyl alcohol dehydrogenase; 4CL, 4-coumarate:CoA ligase; C3H,p-coumarate 3-hydroxylase; C4H, cinnamate 4-hydroxylase; CCoAOMT, caffeoyl-CoAO-methyltransferase; CCR, cinnamoyl-CoA reductase; COMT, caffeic acidO-methyltransferase; HCT, p-hydroxycinnamoyl-CoA: quinate shikimatep-hydroxycinnamo”
• The Regulation of Flavonoid Biosynthesis (2006, background): “The inhibitory activity of FaMYB1 is likely to involve a conserved amino acid sequence associated with transcriptional repression and present also in the AtMYB4 repressor (Aharoni et al., 2001; Jin et al., 2000) (Figure 4.”
• Biosynthesis and Regulation of Phenylpropanoids in Plants (2017, background): “…4 R2R3-MYB repressors include AtMYB3, AtMYB4, AtMYB7 and AtMYB32, all of which possess the conserved EAR repression motif (pdLHLD/LLxiG/S) and the LLsrGIDPxT/SHRxI/L motif in the C-terminal region (Jin et al., 2000; Preston et al. 2004; Dubos et al., 2010; Fornal e et al., 2014; Zhou et al., 2017).”