Repression Domains of Class II ERF Transcriptional Repressors Share an Essential Motif for Active Repression

By Masaru Ohta, Kyoko Matsui, K. Hiratsu, H. Shinshi, M. Ohme-Takagi. The Plant Cell Online, 2001

847 citations recorded by the source corpus.

Subfields: Molecular Biology, Plant Science

View Paper: https://www.semanticscholar.org/paper/0b95b1b8dd9a4b0dcf61de601221fc63da574fb0

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Citations in the corpus

Systemic acquired resistance: turning local infection into global defense. (2013, neutral): “Like the well-studied transcription repressors ERF (ethylene-responsive element binding factor) and AUX/IAA (auxin/indole-3-acetic acid) (99, 129), NIMINs contain the transcription repression motif EAR (L/FDLNL/F(x)P).”
MYB Transcription Factors as Regulators of Phenylpropanoid Metabolism in Plants. (2015, background): “…domains required for repressive activity for example, 26 the ethylene response factor-associated amphiphilic repression (EAR) motif, which 27 actively represses transcription (Ohta et al., 2001), and may recruit chromatin 28 remodeling factors such as TOPLESS (Kagale and Rozwadowski, 2011).”
Molecular characterization of EgMYB1, a putative transcriptional repressor of the lignin biosynthetic pathway (2007, background): “C2, containing the core EAR-motif, was previously shown to play an essential role in active repression [29] [30] [31].”
Comprehending crystalline β-carotene accumulation by comparing engineered cell models and the natural carotenoid-rich system of citrus (2011, neutral): “ZOS3-12 showed an additional feature at its C-terminus: a DLN-box/EAR-motif, which was described as a transcriptional repressor domain (Ohta et al., 2001).”
The AtGenExpress global stress expression data set: protocols, evaluation and model data analysis of UV-B light, drought and cold stress responses. (2007, background): “This immediate onset of a metabolic reprogramming may enable the adjustment of energy homeostasis to the stress conditions which is necessary for a successful stress defence (Ohta et al., 2001; Sakamoto et al., 2004).”
Transcription factors involved in terpenoid indole alkaloid biosynthesis in Catharanthus roseus (2007, background): “All three ZCT proteins contain the LxLxL motif, which has been demonstrated in other zinc finger transcription factors, including proteins that are highly similar in amino acid sequence to the ZCTs, to be involved in active repression ( Ohta et al. 2001; Hiratsu et al. 2003).”
A Conserved Network of Transcriptional Activators and Repressors Regulates Anthocyanin Pigmentation in Eudicots[C][W][OPEN] (2014, background): “…repressive activity (Tamagnone et al., 1998; Jin et al., 2000), such as the ERFassociated amphiphilic repression (EAR) motif, which actively represses transcription (Ohta et al., 2001) and may involve the recruitment of chromatin remodeling factors (e.g., TOPLESS) (Kagale and Rozwadowski, 2011).”
Arabidopsis Cys2/His2-Type Zinc-Finger Proteins Function as Transcription Repressors under Drought, Cold, and High-Salinity Stress Conditions1 (2004, background): “This motif is represented by the signature CX24CX3FX5LX2HX3-5H, consisting of about 30 amino acids and 2 pairs of conserved Cys and His bound tetrahedrally to a zinc ion (Pabo et al., 2001).”
ICE1: a regulator of cold-induced transcriptome and freezing tolerance in Arabidopsis. (2003, methodology): “ment (Ohta et al. 2001).”
Homeodomain proteins: an update (2015, background): “A small repressor motif with conserved leucine residues (core consensus sequence: LxLxL), named ERFassociated amphiphilic repression (EAR), was first identified in ERF transcription factors (ethylene-responsive element binding factors) (Ohta et al. 2001).”
Functions of the ERF transcription factor family in plants (2008, background): “6) that is essential for gene repression (Ohta et al. 2001).”