The influence of cell mechanics, cell-cell interactions, and proliferation on epithelial packing.

By R. Farhadifar, Jens-Christian Röper, B. Aigouy, Suzanne Eaton, Frank Jülicher. Current Biology, 2007

1,276 citations recorded by the source corpus.

Subfields: Cell Biology, Cellular and Molecular Neuroscience, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/4fafe57cabc30f782507d1c294b31df70b2419c8

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Citations in the corpus

Myosin II dynamics are regulated by tension in intercalating cells (2009, background): “This is predicted to sever the plasma membrane and cortical cytoskeleton on both sides of the cell-cell interface (Farhadifar et al., 2007).”
A density-independent rigidity transition in biological tissues (2014, background): “The mechanical energy of a single cell labeled ‘i’ is given by [14, 16]:”
Forces in tissue morphogenesis and patterning. (2013, positive): “The mathematical formulation of this concept in the form of a two-dimensional ‘‘vertex-model’’ and related models has been successfully applied to describe various types of morphogenetic processes in the Drosophila wing disc and germ-band epithelium (Farhadifar et al., 2007; Rauzi et al., 2008; Land”
Unjamming and cell shape in the asthmatic airway epithelium (2015, methodology): “To explain this paradox, we turned to the well-known vertex model, wherein a competition between cell–cell adhesive stresses and cell cortical tension control changes of cell shape 18–20 .”
Live-cell delamination counterbalances epithelial growth to limit tissue overcrowding (2012, methodology): “Delamination is most prevalent in tissue folds after p110 PI(3)K overexpression (coloured white in the z projection).”
Mechanical control of tissue and organ development (2010, background): “This process is mediated by junctional remodeling regulated by PCP signaling molecules, such as Wnt and the small GTPase Rab11, that control cell packing geometry as cells convert from irregular forms into a hexagonal array shortly before hair formation (Classen et al., 2005; Farhadifar et al., 2007”
Nature and anisotropy of cortical forces orienting Drosophila tissue morphogenesis (2008, background): “, as well as topological and packing features, reflecting the balance of cortical elasticity and adhesio”
Physics of adherent cells (2013, background): “For epithelial tissue dominated by direct cell-cell contacts, other approaches are adequate, most prominently vertex models starting from the fact that cell walls are strongly contractile (Farhadifar et al., 2007; Hufnagel et al., 2007; Rauzi et al., 2008; Landsberg et al., 2009; Aegerter-Wilmsen et”
Motility-driven glass and jamming transitions in biological tissues (2015, background): “Recently, Bi and coworkers [7] have demonstrated that the well-studied vertex model for 2-D confluent tissues [8, 12, 22, 31, 33, 49] exhibits a rigidity transition in the limit of zero cell motility.”
Cell flow reorients the axis of planar polarity in the wing epithelium of Drosophila. (2010, positive): “This model takes into account cell mechanics, cell adhesion and cell division (Farhadifar et al., 2007).”