Sudden Death Associated With Short-QT Syndrome Linked to Mutations in HERG
By R. Brugada, K. Hong, R. Dumaine, J. Cordeiro, F. Gaita, M. Borggrefe, T. Menéndez, J. Brugada, G. Pollevick, C. Wolpert and 9 more. Circulation, 2003
846 citations recorded by the source corpus.
Subfields: Cardiology and Cardiovascular Medicine
View Paper: https://www.semanticscholar.org/paper/4f98d2b6fd93751d1753001864a847c8412efdec
How researchers see this paper
The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.
In Cardiology and Cardiovascular Medicine
- Adam P. Hill
- C. Semsarian
- Jamie I. Vandenberg
- M. Perrin
- R. Kass
- J. Nerbonne
- Stefan A. Mann
- J. Towbin
Citations in the corpus
- Molecular physiology of cardiac repolarization. (2005, background): “IKr channel densities, has recently been identified and linked to one form of short QT syndrome (78).”
- hERG K(+) channels: structure, function, and clinical significance. (2012, background): “Although the gene mutations were different in the two families, they both resulted in the same protein change, N588K (80).”
- hERG potassium channels and cardiac arrhythmia (2006, background): “This mutation hastens cardiac repolarization, shortens the QT interval and can cause ventricular fibrillation and sudden deat”
- HRS/EHRA expert consensus statement on the state of genetic testing for the channelopathies and cardiomyopathies: this document was developed as a partnership between the Heart Rhythm Society (HRS) and the European Heart Rhythm Association (EHRA). (2011, background): “However, it is clear that the identical SQT-associated mutation may yield a varied phenotype.(136,139) This indicates that patient-oriented, not family-oriented, clinical decisions must be made.”
- HRS/EHRA expert consensus statement on the state of genetic testing for the channelopathies and cardiomyopathies this document was developed as a partnership between the Heart Rhythm Society (HRS) and the European Heart Rhythm Association (EHRA). (2011, background): “However, it is clear that the identical SQT-associated mutation may yield a varied phenotype.(136,139) This indicates that patient-oriented, not”