Nucleus accumbens shell and core dopamine: differential role in behavior and addiction.

By G. Di Chiara. Behavioural Brain Research, 2002

1,012 citations recorded by the source corpus.

Subfields: Cellular and Molecular Neuroscience, Cognitive Neuroscience, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/4ec268ce2ca2adf41e7bad4c22b949955bbc64ff

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Citations in the corpus

‘Liking’ and ‘wanting’ food rewards: Brain substrates and roles in eating disorders (2009, background): “discussed here, though I and others have recently discussed it elsewhere [33,104,113,114,116,119,120].”
Corticostriatal-hypothalamic circuitry and food motivation: integration of energy, action and reward. (2005, neutral): “[137,179]).”
The addicted human brain: insights from imaging studies. (2003, background): “We hypothesize that, during intoxication, the qualitative difference in activity in the DA-regulated reward circuit (greater and longer-lasting activation compared with the activation by nondrug stimuli) (18) produces a corresponding overactivation of the motivational/drive Figure 3”
Computational models of reinforcement learning: the role of dopamine as a reward signal (2010, background): “Behaviorally, it was also shown that pharmacological manipulations of DA levels in the brain shortly after performance can alter memory consolidation or reconsolidation (Dalley et al. 2005; Fenu and Di Chiara 2003; Hernandez et al. 2005; McGaugh 2002; Robertson and Cohen 2006).”
The neurobiology of positive emotions. (2006, background): “Drugs of abuse (but not aversive stimuli) increase dopamine levels in the accumbens shell region of rat brain (Di Chiara, 2002) 7.”
The tempted brain eats: pleasure and desire circuits in obesity and eating disorders. (2010, positive): “Instead of course, humans and rats alike tend to eat less of food that is unpalatable, and to seek and eat more when available foods are more palatable (Cooper and Higgs, 1994; Dickinson and Balleine, 2002; Grigson, 2002; Kelley et al., 2005b; Levine and Billington, 2004).”
Opioids and the Treatment of Chronic Pain: Controversies, Current Status, and Future Directions (2008, background): “In some cases, however, powerful reinforcement occurs, expressed as efforts to repeat the administration and these reinforcing outcomes may be associated with craving and with positive mood effects such as euphorigenic or pleasurable effects (Di Chiara, 2002; Koob & Bloom, 1988).”
The debate over dopamine’s role in reward: the case for incentive salience (2007, background): “…models that fit such data, attractive familiarity based on a century of associative concepts, and congruence with molecular biology data on neuronal plasticity mechanisms (Berke and Hyman 2000; Di Chiara 2002; Ljungberg et al. 1992; Montague et al. 2004; Schultz 1997, 2006; Wise 2004a).”
The Brain on Drugs: From Reward to Addiction. (2015, background): “…2015 ª2015 Elsevier Inc. of abuse, through their different pharmacological effects, increase the release of DA in the shell subregion of the NAc (Di Chiara, 2002), mimicking the phasic DA neuronal firing that leads to very fast DA increases (Owesson-White et al., 2009) and thus the mechanism…”
Effort-related functions of nucleus accumbens dopamine and associated forebrain circuits (2007, background): “An enormous literature, stretching back several decades, details the involvement of DA systems in the acquisition of tasks involving aversive motivation (Salamone 1994; Santi and Parker 2001; Di Chiara 2002; Huang and Hsiao 2002; Pezze and Feldon 2004; Li et al. 2004).”