Effort-related functions of nucleus accumbens dopamine and associated forebrain circuits

By John Salamone, Mercè Correa, Andrew M. Farrar, S. Mingote. Psychopharmacology, 2007

1,023 citations recorded by the source corpus.

Subfields: Cellular and Molecular Neuroscience, Cognitive Neuroscience, Endocrine and Autonomic Systems

View Paper: https://www.semanticscholar.org/paper/5f8580164c000d5423b5511cc90e8e6a3e49d906

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In Cellular and Molecular Neuroscience

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In Endocrine and Autonomic Systems

Citations in the corpus

Dopamine in motivational control: rewarding, aversive, and alerting (2010, background): “Indeed, DA neurons are critical in motivating effort to achieve high-value goals and in translating knowledge of task demands into reliable motor performance (Berridge and Robinson, 1998; Mazzoni et al., 2007; Niv et al., 2007; Salamone et al., 2007).”
Effort-Based Decision-Making in Major Depressive Disorder: A Translational Model of Motivational Anhedonia (2012, background): “Interference with DA function through lesions or receptor blockade produces a shift towards more LC/LR choices (Denk et al., 2005; Salamone et al., 2007; Salamone, Cousins, McCullough, Carriero, & Berkowitz, 1994), while pharmacological enhancement of DA signaling can increase HC/ HR choices (Bardge”
Reward Processing by the Opioid System in the Brain (2009, neutral): “Nonetheless, accumulating experimental evidence argues against dopamine (DA) mediation of reward processes per se (37, 58, 112, 326, 333, 412).”
The mysterious motivational functions of mesolimbic dopamine. (2012, neutral): “In contrast, appetite suppressants from different classes, including fenfluramine and cannabinoid CB1 antagonists (Salamone et al., 2007; Sink et al., 2008), failed to increase chow intake at doses that suppressed lever pressing.”
Go and no-go learning in reward and punishment: Interactions between affect and effect (2012, background): “, 2009), this pattern is consistentwith a suggestion that dopamine plays a role in action preparation and invigoration (Berridge and Robinson, 1998; Niv et al., 2007; Salamone et al., 2007), a role complementary to its established role in representing a reward prediction error.”
The brain basis of emotion: A meta-analytic review (2012, background): “…and specific way, although there is evidence against Buck’s assertion that specific neurochemicals correspond to “primary affects” (e.g., see Berridge & Robinson 1998; Horvitz 2000; 2002; Salamone et al. 2005; 2007; 2009; Schultz et al. 1993; Wise 2005; for a review, see Barrett et al. 2007a).”
From prediction error to incentive salience: mesolimbic computation of reward motivation (2012, background): “…may still believe that dopamine causes pleasure, the majority opinion in the field seems no longer to accept the dopamine = hedonia view (Wise, 2006; Barbano & Cador, 2007; Berridge, 2007; Daw, 2007; Nicola, 2007; Niv et al., 2007; Salamone et al., 2007; Koob & Volkow, 2010; Aarts et al., 2011).”
Reconsidering Anhedonia in Depression: Lessons from Translational Neuroscience (2010, methodology): “A second line of work has sought to demonstrate a pivotal role for DA in the motivation to pursue rewards, as indexed by overcoming response costs (Salamone et al., 2007).”
Worth the ‘EEfRT’? The Effort Expenditure for Rewards Task as an Objective Measure of Motivation and Anhedonia (2009, background): “In contrast, ventral striatal (nucleus accumbens) DA depletion results in a reduced willingness to expend effort in order to obtain rewards [30,31,32].”
Neurocircuitry of Addiction (2009, background): “…much work suggests that activation of the midbrain dopamine system has multiple roles to give incentive salience to stimuli in the environment (Robinson and Berridge, 1993) to promote performance of goal-directed behavior (Salamone et al, 2007) or activation in general (Le Moal and Simon, 1991).”
Unique properties of mesoprefrontal neurons within a dual mesocorticolimbic dopamine system. (2008, neutral): “, 2002; Berridge, 2007; Di Chiara and Bassareo, 2007), effort (Salamone et al., 2007), or working memory and cognitive control (Aalto et al.”