The c-Myc target gene network.

By C. V. Dang, Kathryn A. O’Donnell, K. Zeller, Tam Nguyen, Rebecca C. Osthus, Feng Li. Seminars in Cancer Biology, 2006

1,191 citations recorded by the source corpus.

Subfields: Materials Chemistry, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/4c231b0348e1e7beaf0e1e23442073bedf4df568

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Citations in the corpus

Double-hit B-cell lymphomas. (2011, neutral): “Kanungo et al13 2006 14/14 (100) None 55 (29-72) NA 13/14 (93) 11/14 (79) 3/14(21) 8/14 (57)¶ NA”
MYC on the Path to Cancer (2012, background): “Given that Myc can repress genes involved in cell-cell and cellsubstratum contacts and that these processes would be diminished as normal cells detach from neighboring cells to undergo mitosis, it should not be surprising that overexpressed Myc would also elicit these phenotypes (Dang et al., 2006).”
MYC as a regulator of ribosome biogenesis and protein synthesis (2010, background): “The deregulated expression of Myc proteins has been implicated in the development of a wide range of cancers (reviewed in Ref”
Activation of a metabolic gene regulatory network downstream of mTOR complex 1. (2010, background): “CMyc has been estimated to regulate up to 15% of all genes, including the genes of glycolysis (Dang et al., 2006).”
The transcription factor Myc controls metabolic reprogramming upon T lymphocyte activation (2011, background): “Consistent with a direct role ofMyc in regulating cell proliferation (Dang et al., 2006; Eilers and Eisenman, 2008), addition of a-KG with HT and PAs failed to promote cell proliferation in Myc-deficient T cells (Figure S7C).”
Transcriptional Amplification in Tumor Cells with Elevated c-Myc (2012, neutral): “Numerous gene expression studies have identified sets of genes whose expression levels are altered by changes in c-Myc levels (Dang et al., 2006; Ji et al., 2011; Kim et al., 2006; Schlosser et al., 2005; Schuhmacher et al., 2001; Zeller et al., 2003).”
Reflecting on 25 years with MYC (2008, background): “Perhaps one of the greatest challenges that researchers face with MYC is that changes of the mRNA expression levels of MYC-regulated genes are relatively small, exacerbating the poor signal-to-noise ratio that was associated with early expression array analyse”
The interplay between MYC and HIF in cancer (2008, background): “In this regard, context-dependent MYC-mediated transcription is crucially important for tumour progressio”