Role of Antibiotic Penetration Limitation in Klebsiella pneumoniae Biofilm Resistance to Ampicillin and Ciprofloxacin

By J. Anderl, M. Franklin, P. Stewart. Antimicrobial Agents and Chemotherapy, 2000

997 citations recorded by the source corpus.

Subfields: Infectious Diseases, Molecular Biology, Molecular Medicine

View Paper: https://www.semanticscholar.org/paper/4c20612c6db1b8a6d37305c66508db41bb91739c

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Infectious Diseases

1. Kim Lewis
2. G. O’Toole
3. Amy Spoering
4. Judith H. Merritt
5. Daniel E. Kadouri
6. P. Stewart
7. Robert E. W. Hancock
8. M. Parsek

In Molecular Biology

1. P. Stewart
2. Kim Lewis
3. D. Lebeaux
4. J. Ghigo
5. C. Beloin
6. Amy Spoering
7. T. Mah
8. M. Parsek

In Molecular Medicine

1. Kim Lewis
2. J. Ghigo
3. D. Lebeaux
4. C. Beloin
5. P. Stewart
6. Amy Spoering
7. N. Kaldalu
8. M. Franklin

Citations in the corpus

• Biofilms and Planktonic Cells of Pseudomonas aeruginosa Have Similar Resistance to Killing by Antimicrobials (2001, background): “For example, fluoroquinolones readily penetrate the biofilm (1, 19, 33, 37).”
• Bacterial biofilm development as a multicellular adaptation: antibiotic resistance and new therapeutic strategies. (2013, background): “On the other hand, it is possible that the matrix can facilitate the accumulation of antibiotic-degrading enzymes such as b-lactamases [36].”
• Specialized Persister Cells and the Mechanism of Multidrug Tolerance in Escherichia coli (2004, methodology): “Previous studies reported rapid equilibration of antibiotics through the colony biofilm (1).”
• A genetic basis for Pseudomonas aeruginosa biofilm antibiotic resistance (2003, background): “The colony biofilm assay exploits the observation that bacterial colonies develop some of the properties of biofilms, including increased antibiotic resistanc”
• Biofilm-Related Infections: Bridging the Gap between Clinical Management and Fundamental Aspects of Recalcitrance toward Antibiotics (2014, background): “In general, preexposure to subinhibitory concentrations of antibiotics (0.2-fold MIC) increases the frequency of persisters with tolerance toward drugs belonging to different classes of antibiotics (ciprofloxacin, gentamicin, oxacillin, and vancomycin) (180).”
• Strategies for combating bacterial biofilms: A focus on anti-biofilm agents and their mechanisms of action (2017, background): “However, the matrix of the biofilm does not act as a mechanical barrier for the antimicrobial agent.(40) This was confirmed by a study which shows that biofilm formed by b-lactamase-defi-”
• Plant Growth-Promoting Rhizobacteria: Context, Mechanisms of Action, and Roadmap to Commercialization of Biostimulants for Sustainable Agriculture (2018, background): “This is an important consideration when applying microbial inoculants to soils where microbes face intense competition and may not be as well adapted to challenging conditions as indigenous soil microbes (Anderl et al., 2000; Mah and O’Toole, 2001; Whiteley et al., 2001; Donlan, 2002; Walters et al.”
• Understanding the Mechanism of Bacterial Biofilms Resistance to Antimicrobial Agents (2017, background): “020063] [PMID: 12194761] [2] Anderl JN, Franklin MJ, Stewart PS.”
• Immobilized viable microbial cells: from the process to the proteome ... or the cart before the horse (2004, critical): “Nevertheless, these factors linked to restricted diffusion in IC structures are insufficient to explain the loss in antimicrobial efficiency of antibiotics against biofilm organisms (Anderl et al., 2000; Konig et al., 2001; Stone et al., 2002).”