Leisure-time physical activity at midlife and the risk of dementia and Alzheimer's disease.

By S. Rovio, I. Kåreholt, E. Helkala, M. Viitanen, Bengt Winblad, J. Tuomilehto, Hilkka Soininen, A. Nissinen, Miia Kivipelto. Lancet Neurology, 2005

1,073 citations recorded by the source corpus.

Subfields: Physical Therapy, Sports Therapy and Rehabilitation, Physiology, Psychiatry and Mental health

View Paper: https://www.semanticscholar.org/paper/4ba8e8fe131922285e33985cd8a09d62d96ff4ab

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In Physical Therapy, Sports Therapy and Rehabilitation

Bruce S. McEwen

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In Psychiatry and Mental health

Citations in the corpus

The diseasome of physical inactivity – and the role of myokines in muscle–fat cross talk (2009, background): “In addition, physical inactivity may also play a role in the development of dementia (Rovio et al. 2005) and even depression (Paffenbarger et al. 1994).”
Positive effect of acute mild exercise on executive function via arousal-related prefrontal activations: An fNIRS study (2014, background): “, 2008), but also lower the risks of age-related cognitive decline and neurological diseases later in life (Lautenschlager et al., 2008; Rovio et al., 2005; Verghese et al., 2003).”
Muscles and their myokines (2011, background): “Physical activity during midlife appears to protect against dementia or cognitive decline and to improve cognitive performance in old adults with memory impairment (Rovio et al., 2005; Sun et al., 2010; Etgen et al., 2010a; Etgen et al., 2010b; Liu-Ambrose et al., 2010; Andel et al., 2008; Lautensch”
Enrichment Effects on Adult Cognitive Development (2008, result): “Unfortunately, however, results obtained thus far are equivocal with regard to whether possession of an e4 allele has a positive effect, negative effect, or no effect on the relationship between physical activity and cognition (Abbott et al., 2004; Larson et al., 2006; Podewils et al., 2005; Rovio e”
Epidemiologic studies of modifiable factors associated with cognition and dementia: systematic review and meta-analysis (2014, methodology): “low physical activity level, two studies used the cut-point of 3 or more times per week [133,145], one used 2 times or more per week [142], one used the criterion of 4 activities per week vs.”
Epidemiology of Alzheimer Disease (2012, neutral): “Although some studies have failed to detect an association between physical activity and dementia (Wang et al. 2002; Wilson et al. 2002a; Verghese et al. 2003b), others have observed a beneficial role (Podewils et al. 2005; Rovio et al. 2005; Larson et al. 2006; Wang et al. 2006 ).”
Brain on stress: How the social environment gets under the skin (2012, background): “It is also wellknown that regular physical activity is an effective antidepressant and protects again cardiovascular disease, diabetes, and dementia (102, 103).”
Physical activity and risk of neurodegenerative disease: a systematic review of prospective evidence (2008, background): “In two studies that examined gene interactions with the ApoE4 genotype, one observed more pronounced associations of physical activity and dementia among ApoE e4 carriers (Rovio et al. 2005) whereas in a different cohort the effects were absent in the carriers (Podewils et al.”
Does physical activity prevent cognitive decline and dementia?: A systematic review and meta-analysis of longitudinal studies (2014, methodology): “Included as part of the meta-analyses were nine studies on dementia and AD (10 cohorts), published up until 2007 [23,35-42].”
Central effects of stress hormones in health and disease: Understanding the protective and damaging effects of stress and stress mediators. (2008, background): “Concerning physical activity, it is not necessary to become an extreme athlete, and seemingly any amount of moderate physical activity helps (Bernadet, 1995; Rovio et al., 2005).”
Stress- and Allostasis-Induced Brain Plasticity (2011, neutral): “For the elderly, community centers and activities that promote social interactions and physical activity have been demonstrated to be beneficial across a number of domains (63, 64).”
The Risks of Ageism Model: How Ageism and Negative Attitudes toward Age Can Be a Barrier to Active Aging (2017, background): “Several studies suggest the benefits of being physically active, including reduced likelihood of chronic diseases (Berlin & Colditz, 1990), cognitive decline (Lautenschlager et al., 2008; Rovio et al., 2005), and mental health issues (Lawlor & Hopker, 2001; Netz, Wu, Becker, & Tenenhaum, 2005).”
Capitalizing on cortical plasticity: influence of physical activity on cognition and brain function. (2007, background): “... of self-report versus more objectively measured physical activities and fitness; the relative contribution of social, intellectual and physical factors to different everyday activities [18]; the role of physical activity duration, intensity, and frequency [19]; the nature of the components of co”