Age and disease related changes in intestinal bacterial populations assessed by cell culture, 16S rRNA abundance, and community cellular fatty acid profiles

By M. Hopkins, R. Sharp, G. Macfarlane. Gut, 2001

594 citations recorded by the source corpus.

Subfields: Food Science, Infectious Diseases, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/4a7ea87d8b5964fb8f56425a39ded813945ada71

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Citations in the corpus

Comparative Analysis of Pyrosequencing and a Phylogenetic Microarray for Exploring Microbial Community Structures in the Human Distal Intestine (2009, unknown): “on decreased microbial diversity in general [2,3], and depletion of beneficial bacteria such as bifidobacteria in particular [4],”
Characterization of Bacterial Communities in Feces from Healthy Elderly Volunteers and Hospitalized Elderly Patients by Using Real-Time PCR and Effects of Antibiotic Treatment on the Fecal Microbiota (2004, background): “Bifidobacteria are regarded as being protective species in the large intestine, but there are indications that their numbers decline in older people, while the number of potentially harmful enterobacteria increases (16, 17, 19 , 20, 22, 32, 33).”
Bifidobacteria and Their Role as Members of the Human Gut Microbiota (2016, background): “Fifteen out of the 20 patients remained in remission throughout the trial, suggesting that administration of this bacterial cocktail is beneficial in maintaining remission from ulcerative colitis (Venturi et al., 1999; Gionchetti et al., 2000).”
The gut flora as a forgotten organ (2006, background): “EMBO reports VOL 7 | NO 7 | 2006 ©2006 EUROPEAN MOLECULAR BIOLOGY ORGANIZATION review 688 revie”
The first 1000 cultured species of the human gastrointestinal microbiota (2014, background): “The abundance of this bacterial group increases with age, but it remains subdominant and in elderly subjects represents about 1% of the total gastrointestinal microbiota (Hopkins et al., 2001).”
Bacterial metabolism and health‐related effects of galacto‐oligosaccharides and other prebiotics (2007, background): “For example, a number of investigations have shown that colonic bifidobacterial populations decline in older people, while there are increased numbers of potentially harmful clostridia and enterobacteria (Gavini et al. 2001; Hopkins et al. 2001; Bartosch et al. 2005).”
Mucosa-Associated Bacteria in the Human Gastrointestinal Tract Are Uniformly Distributed along the Colon and Differ from the Community Recovered from Feces (2002, background): “Such studies revealed that the predominant bacterial community in mammalian feces is stable in time, host specific, affected by ageing, and not altered after consumption of certain probiotic strains (11, 21, 24, 25, 28, 29).”
Diversity of the human gastrointestinal tract microbiota revisited. (2007, background): “…amplicons from an intestinal sample generally describes only the dominant fractions of the microbiota (Zoetendal et al., 2006), and it is known that Proteobacteria have low abundance in the human gastrointestinal tract (Hopkins et al., 2001), such low recovery of this phylum had to be expected.”
The Firmicutes/Bacteroidetes ratio of the human microbiota changes with age (2009, background): “Discussion The microbiota of the large intestine plays an important role in host metabolism and maintenance of host health [19].”