Human mesenchymal stem cells modulate allogeneic immune cell responses.
By Sudeepta Aggarwal, M. Pittenger. Blood, 2005
775 citations recorded by the source corpus.
Subfields: Genetics, Hematology, Molecular Biology
View Paper: https://www.semanticscholar.org/paper/49dc233c1da8b7e5343b90f98a49f75e3f573f82
How researchers see this paper
The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.
In Genetics
- Aline M. Betancourt
- Ruth S. Waterman
- Suzanne L. Tomchuck
- Sarah L. Henkle
- Maria Ester Bernardo
- W. Fibbe
In Hematology
In Molecular Biology
Citations in the corpus
- A New Mesenchymal Stem Cell (MSC) Paradigm: Polarization into a Pro-Inflammatory MSC1 or an Immunosuppressive MSC2 Phenotype (2010, methodology): “cytokines, chemokines, and extracellular matrix proteins [3,5].”
- Extracellular matrix: a dynamic niche component during cancer progression (2012, neutral): “This is an especially important point, as MSCs can exert pleiotropic effects on inflammation (Aggarwal and Pittenger, 2005; Ripoll et al., 2011; Singer and Caplan, 2011).”
- Mesenchymal Stem Cells Secrete Immunologically Active Exosomes (2014, neutral): “Tregs are adaptive immune cells that are modulated by activated antigen presenting cells (APCs) such as dendritic cells, macrophages, and monocytes, and the activation of APCs, in turn, could be modulated by MSCs [9].”
- Cancer immunotherapy comes of age (2011, neutral): “For example, mesenchymal stem cells block proliferation and function of effector T cell”
- Bone marrow stromal cells attenuate sepsis via prostaglandin E2—dependent reprogramming of host macrophages to increase their interleukin-10 production (2008, neutral): “BMSCs have been shown to produce prostaglandin E 2 and possibly affect other immune cells via EP1–EP4 receptor”
- Mesenchymal stromal cells: sensors and switchers of inflammation. (2013, neutral): “The suppression of T cell proliferation involves both CD4 + and CD8 + T cells; IFN-g production and cytotoxicity are also inhibited in a dose-dependent manner (Krampera et al., 2003; Aggarwal and Pittenger, 2005).”