Structure, dynamics and functions of promyelocytic leukaemia nuclear bodies

By R. Bernardi, P. Pandolfi. Nature reviews. Molecular cell biology, 2007

923 citations recorded by the source corpus.

Subfields: Hematology, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/496508a97eb44dd2b9a3a63789ea38e250033d18

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Hematology

1. T. Suda

In Molecular Biology

1. Yongdae Shin
2. Arkaitz Carracedo
3. C. Brangwynne
4. P. Pandolfi
5. T. Suda
6. Keisuke Ito
7. C. Lima
8. R. Evans

Citations in the corpus

• A PML-PPARδ pathway for fatty acid oxidation regulates haematopoietic stem cell maintenance (2012, background): “The PML (promyelocytic leukemia) tumor-suppressor gene, originally cloned at the break point of the t(15;17) chromosomal translocation of acute promyelocytic leukemia, has a key role in the maintenance of HSCs16.”
• The SUMO pathway: emerging mechanisms that shape specificity, conjugation and recognition (2010, background): “This process is exemplified by the base excision repair enzyme thymine DNA glycosylase (TDG), promyelocytic leukaemia protein (PML) and the transcription factor DAXX, and has been reviewed previousl”
• Biogenesis and Function of Nuclear Bodies (2011, background): “nuclear domain 10, ND10), is essential for PML-NB formation since human leukemia and solid tumors cells in which the PML gene is inactivated and pml-/- mouse cells fail to assemble PML-NBs [24].”
• Genome-wide identification of Polycomb-associated RNAs by RIP-seq (2010, background): “Because misregulation of Polycomb proteins is often associated with cancer, we intersected PRC2-interacting RNAs with oncogene and tumor suppressor loci (Sparmann and van Lohuizen, 2006; Bernardi and Pandolfi, 2007; Miremadi et al., 2007; Rajasekhar and Begemann, 2007; Simon and Lange, 2008).”
• Phase Transitions in the Assembly of Multi-Valent Signaling Proteins (2012, background): “These include promyelocytic leukaemia nuclear bodies, Cajal bodies, P bodies and P granule”
• Liquid phase condensation in cell physiology and disease (2017, background): “Given the ability of a small subset of proteins to drive phase separation, how might these proteins recruit other molecules into the droplet? Important insights have come from recent work using repetitive domains of the binding partners small ubiquitin-like modifier (SUMO) and the SUMO interacting m”