Solid freeform fabrication of three-dimensional scaffolds for engineering replacement tissues and organs.

By K. Leong, C. Cheah, C. K. Chua. Biomaterials, 2003

1,055 citations recorded by the source corpus.

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

Three-Dimensional Scaffolds for Tissue Engineering Applications: Role of Porosity and Pore Size (2013, neutral): “16,20,21 Although rapid prototyping techniques may have several advantages, some limitations and challenges still remain FIG.”
Collagen-hydroxyapatite composites for hard tissue repair. (2006, methodology): “Furthermore, the easy removal of ice crystals compared to porogens, used in conventional polymeric-porogen leaching, eliminates any dimensional restrictions (Leong et al., 2003).”
Application of inkjet printing to tissue engineering (2006, background): “Hierarchical design of the scaffolds with microto millimeter features have demonstrated that enhanced control over mechanical properties, biological effects and degradation kinetics of the scaffolds is possible [12].”
Three-Dimensional Cell Culture Matrices: State of the Art (2008, methodology): “Currently, the minimum feature size is restricted to approximately 100 to 500 mm, depending on the fabrication process selected.(176,186,187) Matrices manufactured using SFF do not possess distinct nano-scale features, because the minimum resolution of most fabrication techniques is larger than 100 ”