Identification, Timing, and Signal Specificity of Pseudomonas aeruginosa Quorum-Controlled Genes: a Transcriptome Analysis

By M. Schuster, C. Lostroh, T. Ogi, E. P. Greenberg. Journal of Bacteriology, 2003

1,145 citations recorded by the source corpus.

Subfields: Ecology, Genetics, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/473ecc74fb82b63cf1043d34985dcb0540e1a2db

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Citations in the corpus

The hierarchy quorum sensing network in Pseudomonas aeruginosa (2014, background): “…studies based on lasI and rhlI mutants revealed that the regulons are on a continuum, with some genes that respond dramatically well to OdDHL (e.g. lasA), some with BHL specificities (e.g. rhlAB), and some equally well to both signals (Schuster and Greenberg, 2006; Schuster et al., 2003).”
Identification of FleQ from Pseudomonas aeruginosa as a c-di-GMP-responsive transcription factor (2008, methodology): “RNA was isolated and cDNA synthesized using previously published procedures (Schuster et al., 2003).”
Quorum sensing: cell-to-cell communication in bacteria. (2005, background): “This indicates that the tandem network architecture indeed produces a temporally ordered sequence of gene expression that may be critical for the ordering of early and late events in a successful infection (Schuster et al. 2003, Whiteley et al. 1999).”
The phenazine pyocyanin is a terminal signalling factor in the quorum sensing network of Pseudomonas aeruginosa (2006, methodology): “Preparation of labelled cDNA and processing of P. aeruginosa GeneChip arrays were performed as previously described (Schuster et al., 2003).”
Human Host Defense Peptide LL-37 Prevents Bacterial Biofilm Formation (2008, background): “This resulted in a downregulation of more than 50 genes (Table 1) that are part of the respective regulons (45, 54).”
A Database of Bacterial Lipoproteins (DOLOP) with Functional Assignments to Predicted Lipoproteins (2006, methodology): “(ii) Next, we identiﬁed up-regulated and down-regulated genes in P. aeruginosa under quorum-sensing conditions using the data set that was previously published (49).”
Look who's talking: communication and quorum sensing in the bacterial world (2007, background): “At least 6% (over 300 genes) of the 6.3 MB P. aeruginosa genome is AHL-regulated via the las and rhl quorum sensing systems (Hentzer et al. 2003; Schuster et al. 2003; Wagner et al. 2004).”
Screening for Quorum-Sensing Inhibitors (QSI) by Use of a Novel Genetic System, the QSI Selector (2005, background): “Although induction and repression of QS-controlled genes formed a continuum throughout the growth cycle (40), a majority of the genes are maximally regulated at the transition to stationary phase (25); hence, growth was followed to OD600 of 2.”
Indole as an intercellular signal in microbial communities. (2010, background): “aeruginosa were believed to regulate the gene expression in a specific temporal order (Schuster et al., 2003), and a temporal transcriptomic study of AI-2 signal showed the temporal expression of virulence genes (Bansal et al.”