Stem cell therapy in a caprine model of osteoarthritis.

By Mary Murphy, D. J. Fink, E. B. Hunziker, Frank Barry. Arthritis & Rheumatism, 2003

1,150 citations recorded by the source corpus.

Subfields: Genetics, Rheumatology, Urology

View Paper: https://www.semanticscholar.org/paper/4695931e8dc6a4f1986a6c1e5986d20aab610720

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Genetics

1. A. Caplan
2. Frank Barry
3. D. Prockop

In Rheumatology

1. Frank Barry
2. A. Caplan

In Urology

1. Frank Barry
2. A. Caplan

Citations in the corpus

• Mesenchymal stem cells avoid allogeneic rejection (2005, methodology): “2PE); an E) D40L/ CD154 (a tib dy 24-31-FITC), F) CD95L (FasL) negative (antibody NOK-1-PE) Fi ure 2 Human MSC cultured according to [106, 107] are A) MHC-I positive (HLA-A,B,C, antibody W6/32-FITC), B) MHC class II negative (HLA-DR, antibody LN-3-PE); C) CD14 negative (antibody MEM-18-FITC), D) CD8”
• Adult mesenchymal stem cells for tissue engineering versus regenerative medicine (2007, methodology): “…have been used in animal models to affect heart infarct ischemia (Shake et al., 2002), stroke ischemia (Li et al., 2005), meniscus regeneration (Murphy et al., 2003), tendinitis (Harman et al., 2006), and spinal cord interruption (contusion or cuts), (Lange et al., 2005; Keilhoff et al., 2006).”
• Mesenchymal stem cells as trophic mediators (2006, background): “Studies by Frank Barry and colleagues detail the use of an adult goat model to document the MSC-mediated regeneration of meniscus [Murphy et al., 2003].”
• Same or Not the Same? Comparison of Adipose Tissue-Derived Versus Bone Marrow-Derived Mesenchymal Stem and Stromal Cells (2012, neutral): “MSCs were shown to demonstrate therapeutic efficacy in animal models of meniscus injury [69], neurological disorders [70], myocardial infarction (MI) [71], lung injury [72], ischemic acute renal failure [73], and others.”
• Why are MSCs therapeutic? New data: new insight (2009, background): “In addition, in a goat model of severe osteoarthritis, MSCs injected into knee joints in a hyaluronan delivery vehicle showed the regeneration of the surgically amputated meniscus [42].”
• Mesenchymal stem cells: clinical applications and biological characterization. (2004, background): “In an animal model of osteoarthritis involving injury to the meniscus delivery of stem cells by intraarticular injection resulted in engraftment of those cells on the meniscus, fat pad and synovium (Fig. 4) with regeneration of meniscal tissue and protection of the cartilage ( Murphy, Fink, Hunziker”