Obesity and the human microbiome

By Ruth E. Ley. Current Opinion in Gastroenterology, 2010

779 citations recorded by the source corpus.

Subfields: Epidemiology, Infectious Diseases, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/45d7fe771e129f18058b658af4d6ec446dd94072

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Citations in the corpus

High Fat Diet-Induced Gut Microbiota Exacerbates Inflammation and Obesity in Mice via the TLR4 Signaling Pathway (2012, background): “Several recent studies have provided compelling evidence to suggest an association between the gut microbiome and body weight regulation [25,26].”
The Role of Microbial Amino Acid Metabolism in Host Metabolism (2015, background): “However, it should be noted that there have also been contradictory studies that did not find a shift in the Firmicutes-Bacteroidetes ratio [74,75].”
Marine Animal Microbiomes: Toward Understanding Host–Microbiome Interactions in a Changing Ocean (2017, background): “In fact, for many terrestrial animals, new reports of microbial symbioses provide insights into the variety of genetic and biochemical interactions and the ways that microorganisms contribute to animal health, behavior, and ecology (e.g., Ley, 2010; Cho and Blaser, 2012).”
Composition and energy harvesting capacity of the gut microbiota: relationship to diet, obesity and time in mouse models (2010, result): “In addition, a number of follow-up studies in humans have provided variable findings with respect to changes in the gut microbiota in obese individuals and placed less emphasis on changes in the proportions of Firmicutes and Bacteroidetes in obesity.(5) 6 24e28 Moreover, few reports have examined th”
Chronic Inflammation in Obesity and the Metabolic Syndrome (2010, result): “[111] R.”
Composition of the adult digestive tract bacterial microbiome based on seven mouth surfaces, tonsils, throat and stool samples (2012, background): “In disease, with breach of the mucosal barrier, commensal bacteria can become a chronic inflammatory stimulus to adjacent tissues [2,3] as well as a source of immune perturbation in conditions such as atherosclerosis, type 2 diabetes, non-alcoholic fatty liver disease, obesity and inflammatory bowel”
Diet-Induced Dysbiosis of the Intestinal Microbiota and the Effects on Immunity and Disease (2012, background): “Restoring the microbiota may attenuate the metabolic conditions associated with obesity and help individuals maintain a healthy weight [90].”
Metabolic modeling of species interaction in the human microbiome elucidates community-level assembly rules (2013, background): “Specifically, recent studies of the microbiome have found tremendous variation among healthy individuals (1) and demonstrated clear associations between species composition and several host phenotypes including obesity (4, 5), inflammatory bowel disease (IBD) (2), and diabetes (6), as well as with e”
Periodontitis and diabetes: a two-way relationship (2011, background): “The tenets of ‘infectobesity’ suggest that the gut microbiota of obese individuals may be more efficient at extracting energy from a given diet than that of lean individuals [70, 71], and gut microorganisms can affect host metabolism, influencing inflammation and insulin resistance [72].”
The first 1000 cultured species of the human gastrointestinal microbiota (2014, background): “…in the gastrointestinal microbiota is complex: while the reduced abundance of the Bacteroidetes in some cases is associated with obesity (Ley, 2010) and irritable bowel syndrome (Rajili c-Stojanovi c et al., 2011), this bacterial group appears to be enriched in patients suffering from…”
The Impact of the Gut Microbiota on Human Health: An Integrative View (2012, neutral): “The Obese Microbiota: Interactions with the Immune System Obesity is a physiological state that has emerged as a major health concern in populations that have adopted a Western diet and is closely tied to the microbiota (Ley, 2010).”
Intestinal microbiota in human health and disease: the impact of probiotics (2011, background): “…(on diet and physical activity) qPCR Obese adolescents on diet with a high weight-loss: : Total bacteria : B. fragilis group : C. leptum group : B. catenulatum group ; C. coccoides group ; Lactobacillus group Santacruz et al. (2009) and Delzenne 2009; Ley 2010; Vrieze et al. 2010).”
Targeting gut microbiota in obesity: effects of prebiotics and probiotics (2011, background): “The bacterial changes at the taxonomic level in individuals with obesity have been described elsewhere”
Animals in a bacterial world, a new imperative for the life sciences (2013, background): “In mammals, SCFAs affect fat deposition, appetite-related hormone titers, and food consumption, which in turn can modulate the composition of the microbiota and have major consequences for health and behavior (76, 77).”