A genome-wide association study of global gene expression

By A. Dixon, L. Liang, Miriam Moffatt, Wei Chen, S. Heath, Kenny C. C. Wong, Jenny C. Taylor, E. Burnett, Ivo G. Gut, Martin Farrall and 3 more. Nature Genetics, 2007

1,046 citations recorded by the source corpus.

Subfields: Genetics, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/456d1618a29f6ab257e914e4129768f5c593a81b

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Citations in the corpus

Progress and Promise of Genome-Wide Association Studies for Human Complex Trait Genetics (2011, background): “Recently, GWASs have been conducted on mRNA levels, themselves quantitative traits, in expression QTL (eQTL) mapping studies (see Table 1) (e.g., Dixon et al. 2007; Goring et al. 2007; Stranger et al. 2007a,b; Dimas et al. 2009).”
Genotype Imputation (2009, background): “(28), we mapped, on average, 10% more genome-wide association peaks to the locus surrounding each transcript than before imputation (L.”
Sex-specific genetic architecture of human disease (2008, background): “With the availability of many data sets with both dense SNP typing and measurements of global gene expression in the same individual”
Genetics and Beyond – The Transcriptome of Human Monocytes and Disease Susceptibility (2010, methodology): “For Dixon et al [2], data were extracted from Table S1 and trans eQTLs were excluded.”
Protein networks in disease. (2008, background): “data have been generated in humans, including a number of eQTL studies (Dixon et al. 2007; Goring et al. 2007; Stranger et al. 2007).”
GENETICS AND PATHOGENESIS OF INFLAMMATORY BOWEL DISEASE (2016, background): “The resultant gene expression profile and that of eQTL can be further used to study potential gene-gene interactions and networks (59).”
Mapping the Genetic Architecture of Gene Expression in Human Liver (2008, background): “Several recent studies have been published that examine the extent of genetic control in blood [20–22], brain [23], and adipose [21] gene expression via genetic association testing.”
Meta-Analysis Increases to 71 the Tally of Confirmed Crohn’s Disease Susceptibility Loci (2010, methodology): “These analyses were (i) interrogation of a publicly available expression quantitative trait loci (eQTL) databas”
Common variants at 7p21 are associated with frontotemporal lobar degeneration with TDP-43 inclusions (2010, methodology): “We queried the mRNA-by-SNP browser (see URLs ; last accessed 6 June 2009), for genetic regulators of TMEM106B expression (eSNPs) in lymphoblastoid cell line”
Aberrant Mucin Assembly in Mice Causes Endoplasmic Reticulum Stress and Spontaneous Inflammation Resembling Ulcerative Colitis (2008, background): “Conversely, some local factors may ameliorate the consequences of ER stress; for example, IL-10 has recently been shown to modulate the UPR in intestinal cells by inhibiting nuclear translocation of the ATF6 transcription factor [59].”