Childhood maltreatment predicts adult inflammation in a life-course study

By A. Danese, C. Pariante, Avshalom Caspi, Alan H. Taylor, Richie Poulton. Proceedings of the National Academy of Sciences of the United States of America, 2007

1,244 citations recorded by the source corpus.

Subfields: Behavioral Neuroscience, Clinical Psychology, Pediatrics, Perinatology and Child Health

View Paper: https://www.semanticscholar.org/paper/454e58c4eed16ea976d6fa3a9ec9971b016269f7

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Behavioral Neuroscience

1. Andrew H. Miller
2. C. Nemeroff
3. Bruce S. McEwen
4. Charles L Raison
5. A. Danese
6. George M. Slavich
7. L. Capuron
8. Michael R. Irwin

In Clinical Psychology

1. Bruce S. McEwen
2. C. Nemeroff
3. Avshalom Caspi
4. Terrie E. Moffitt
5. A. Danese
6. Andrew H. Miller
7. James J. Heckman
8. Charles L Raison

In Pediatrics, Perinatology and Child Health

1. C. Nemeroff
2. A. Danese
3. Bruce S. McEwen
4. Andrew H. Miller
5. Charles L Raison
6. A. Kalil
7. Shanta R. Dube
8. V. Felitti

Citations in the corpus

• More than a feeling: A unified view of stress measurement for population science (2018, background): “, 2010), biological pathways such as chronic inflammation in adulthood (Slopen et al., 2010; Surtees et al., 2003; Danese et al., 2007) and telomere shortening (Hanssen et al.”
• So depression is an inflammatory disease, but where does the inflammation come from? (2013, positive): “Data from the Dunedin Multidisciplinary Health and Development Study in New Zealand, a longitudinal study following 1,000 participants from birth to 32 years, have demonstrated that individuals experiencing stress in childhood resulting from maltreatment, abuse, social isolation and economic hardshi”
• Inflammation and Its Discontents: The Role of Cytokines in the Pathophysiology of Major Depression (2009, positive): “A rich database also indicates that chronic stress, including caregiving, marital discord, and perceived stress, is associated with increases in the acute phase protein, C-reactive protein (CRP), as well as IL-6 and other inflammatory mediators (90-92).”
• Identifying the women at risk of antenatal anxiety and depression: A systematic review (2016, background): “As both systems are over-stimulated during normal pregnancy, this may make mothers more susceptible to depression in the context of previous exposure to childhood maltreatment (Danese et al., 2007; Heim et al., 2008; Pariante et al., 2014; Pariante and Lightman, 2008; RobertsonBlackmore et al., 2013”
• Inflammation: The Common Pathway of Stress-Related Diseases (2017, background): “…and TNFα directly stimulate the pituitary-adrenal axis, resulting in increased serum levels of adrenocorticotropic hormone (ACTH) and GCs, which in turn inhibit the production of these pro-inflammatory factors (Alley et al., 2006; Danese et al., 2007; Steptoe et al., 2007; Miller et al., 2008).”
• Adverse childhood experiences, allostasis, allostatic load, and age-related disease. (2012, background): “These changes appeared to be independent of objective and subjective measures of adult stress exposure [134], suggesting that they were not simply due to continuities in risky environments between childhood and adult life.”
• Early-childhood poverty and adult attainment, behavior, and health. (2010, background): “The opposite is true of body mass—very early income appears to matter more than income after the birth year, a result explored in some depth in Ziol-Guest, Duncan, and Kalil (2009). This finding of the particular importance of income during the prenatal and birth years for adult BMI may support the ”
• Effect of Compassion Meditation on Neuroendocrine, Innate Immune and Behavioral Responses to Psychosocial Stress (2008, background): “…that these pathways may be a mechanism by which stress and depression are transduced into medical illness (Lutgendorf et al., 1999; Goebel et al., 2000; Bierhaus et al., 2003; Kiecolt-Glaser et al., 2003; Kiecolt-Glaser et al., 2005; McDade et al., 2006; Pace et al., 2006; Danese et al., 2007).”
• Brain-gut interactions in inflammatory bowel disease. (2013, background): “There is a link between early-life stress and depression that may predispose to increased inflammation both under baseline conditions and following stress (79).”
• EARLY CHILDHOOD INVESTMENTS SUBSTANTIALLY BOOST ADULT HEALTH (2014, background): “A large body of evidence shows that adult illnesses are more prevalent and problematic among those who have experienced adverse early life conditions (6, 7).”