Cross-presentation by dendritic cells
By O. Joffre, É. Segura, A. Savina, S. Amigorena. Nature reviews. Immunology, 2012
1,522 citations recorded by the source corpus.
Subfields: Immunology
View Paper: https://www.semanticscholar.org/paper/424ddfe47b445c5d6c562ed38d860248ef46f40a
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In Immunology
Citations in the corpus
- Immunology of Psoriasis (2014, background): “During cross-presentation, endogenous antigens are processed for additional CD4+ T cell responses, which may be highly desirable for generating effective and long-lived immune responses (25).”
- Dendritic-cell-based therapeutic cancer vaccines. (2013, background): “…components necessary for the induction of such CD8+ T cells include (1) the presentation of antigen by appropriate antigen-presenting cells (APCs) (Joffre et al., 2012; Lizée et al., 2013) and (2) the generation of CD4+ T cells producing cytokines helping CD8+ T cell proliferation and…”
- Present Yourself! By MHC Class I and MHC Class II Molecules (2016, background): “There is more than one mechanism by which ingested antigens can be cross-presented but one likely involves cytosolic transfer of antigen from the phagosome into the cytosol for degradation by the proteasome[83,84].”
- Cancer immunotherapy via dendritic cells (2012, positive): “Earlier studies of human cutaneous DCs demonstrated their phenotypic and functional heterogeneity with regard to cellular immunity and priming of highly efficient CTLs [26].”
- Immunological Principles Guiding the Rational Design of Particles for Vaccine Delivery. (2017, neutral): “Materials within the endosomes can be degraded into peptide fragments, allowing import into the endoplasmic reticulum (ER) and presentation via classical MHC class I pathways.(36) Alternatively, degraded peptides can be imported directly back into phagosomes (vacuolar pathway) for MHC I loading and ”