Activity‐dependent regulation of energy metabolism by astrocytes: An update
By Luc Pellerin, Anne-Karine Bouzier-Sore, Agnès Aubert, S. Serres, M. Merle, R. Costalat, Pierre J. Magistretti. Glia, 2007
825 citations recorded by the source corpus.
Subfields: Cellular and Molecular Neuroscience, Developmental Neuroscience, Neurology
View Paper: https://www.semanticscholar.org/paper/422be6f848f18cba41caa48256a9e666d2ff4762
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Citations in the corpus
- A cellular perspective on brain energy metabolism and functional imaging. (2015, background): “…neuronal activity (Boumezbeur et al., 2010; Bouzier et al., 2000; BouzierSore et al., 2006; Itoh et al., 2003; Qu et al., 2000; Schurr et al., 1997; Schurr and Gozal, 2011; Serres et al., 2005; also reviewed in Bélanger et al., 2011a; Pellerin et al., 2007; Pellerin and Magistretti, 2012).”
- Astrocytes: biology and pathology (2009, background): “Other lines of evidence indicate that during hypoglycemia, astrocyte glycogen breaks down to lactate that is transferred to adjacent neural elements (both synapses in gray matter and axons in white matter) where it is used aerobically as fuel [27, 28, 181, 252].”
- Decoding Alzheimer's disease from perturbed cerebral glucose metabolism: implications for diagnostic and therapeutic strategies. (2013, background): “It has been demonstrated that glycogen could be used to provide lactate for neuronal metabolism during hypoglycemia (Brown and Ransom, 2007; Pellerin et al., 2007), which may suggest astrocytes play critical roles in both normal glucose supply and hypoglycemic conditions.”
- The bioenergetic and antioxidant status of neurons is controlled by continuous degradation of a key glycolytic enzyme by APC/C–Cdh1 (2009, background): “dtd" [ ]> Neurons are known to have a lower glycolytic rate than astrocytes and when stressed they are unable to upregulate glycolysi”
- Astrocyte reactivity and reactive astrogliosis: costs and benefits. (2014, background): “The membrane of astrocyte processes is often in aposition also with other cell types in the CNS, such as neurons, endothelial cells, or pericytes, and this forms the basis for extensive cell-cell communication and processes, such as recycling of neurotransmitters or nutrition of neurons (181, 200, 2”
- Brain energy metabolism: focus on astrocyte-neuron metabolic cooperation. (2011, background): “The stimulation of astrocytic glucose utilization by glutamate was subsequently confirmed by several independent groups (reviewed in Pellerin et al., 2007; Barros and Deitmer, 2010).”
- BRAIN FUEL METABOLISM, AGING AND ALZHEIMER’S DISEASE (2010, background): “Coupling of neuron and astrocyte function is an important component of the energy cost of brain function but this, too, is not always included in the modeling [13,14].”
- Targeting lactate metabolism for cancer therapeutics. (2013, background): “Furthermore, a second-generation MCT1/ MCT2 inhibitor (AZD3965) is currently in Phase I clinical trials for advanced solid tumors and for diffuse large B cell lymphoma (86).”
- Regulation of pyruvate metabolism and human disease (2013, methodology): “In astrocytes, the ATP generated by aerobic glycolysis is used to fuel glutamate uptake by excitatory amino acid transporter [192, 235, 236].”
- STAT3 is a critical regulator of astrogliosis and scar formation after spinal cord injury (2008, background): “Signaling regulation of astrocyte roles after SCI Astrocytes exert many activities essential to normal CNS function (Kettenmann and Ransom, 2004; Christopherson et al., 2005; Gensert and Ratan, 2006; Iadecola and Nedergaard, 2007; Pellerin et al., 2007).”