DREADDs (designer receptors exclusively activated by designer drugs): chemogenetic tools with therapeutic utility.

By D. Urban, Bryan L. Roth. Annual Review of Pharmacology and Toxicology, 2015

641 citations recorded by the source corpus.

Subfields: Animal Science and Zoology, Cellular and Molecular Neuroscience, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/42060efc7b2f0cbf21aa256f288cba0d3eaea2ae

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Animal Science and Zoology

1. Bryan L. Roth

In Cellular and Molecular Neuroscience

1. Bryan L. Roth
2. M. Krashes
3. S. Waddell

In Molecular Biology

1. Bryan L. Roth

Citations in the corpus

• A New DREADD Facilitates the Multiplexed Chemogenetic Interrogation of Behavior (2015, positive): “It has also been reported by many labs that both the behavioral and electrophysiological effects of CNO-mediated DREADD activation can persist for several hours following a single injection in a manner predicted by its pharmacokinetic properties (Urban and Roth, 2015).”
• DREADDs for Neuroscientists (2016, methodology): “Current DREADDs As shown in Table 1 (for recent reviews, see Sternson and Roth, 2014;Urban and Roth, 2015; English and Roth, 2015), there now exist many GPCR-based chemogenetic tools.”