RNA granules: post-transcriptional and epigenetic modulators of gene expression
By Paul Anderson, N. Kedersha. Nature reviews. Molecular cell biology, 2009
883 citations recorded by the source corpus.
Subfields: Molecular Biology
View Paper: https://www.semanticscholar.org/paper/405422331d69978ea353a8fe16dc601a753dfa0e
How researchers see this paper
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In Molecular Biology
- R. Parker
- C. Brangwynne
- Yongdae Shin
- S. Alberti
- David S. W. Protter
- Paul Anderson
- N. Kedersha
- P. Ivanov
Citations in the corpus
- Spatiotemporal control of intracellular phase transitions using light-activated optoDroplets (2016, neutral): “Among dozens of examples include nuclear bodies such as nucleoli, Cajal bodies, and PML bodies, and cytoplasmic germ granules, stress granules and processing bodies ((Mao et al., 2011), (Anderson and Kedersha, 2009), (Buchan and Parker, 2009), (Handwerger and Gall, 2006)).”
- Liquid-Liquid Phase Separation in Disease. (2019, background): “PBs are constitutive compartments, whereas SGs form upon exposure of cells to various forms of stress (10, 30).”
- Converging mechanisms in ALS and FTD: Disrupted RNA and protein homeostasis (2013, neutral): “These granules include processing bodies (P bodies), which contain RNA decay machinery (Buchan and Parker, 2009), stress granules, which contain translationmachinery (Anderson and Kedersha, 2009), and transporting RNP granules, which contain RNAs to be locally translated (Kiebler and Bassell, 2006).”
- Alternative RNA Conformations: Companion or Combatant (2022, background): “These granules are responsible for regulating the gene expression by means of compartmentalization and by increasing the specific biomolecule concentration through altering the reaction specificities and kinetics [65,67,68].”
- G3BP–Caprin1–USP10 complexes mediate stress granule condensation and associate with 40S subunits (2016, background): “Stress granules (SGs) are dynamic assemblies of stalled 48S preinitiation complexes, triggered by stresses causing polysome disassembly (Anderson and Kedersha, 2008, 2009; Buchan and Parker, 2009; Erickson and Lykke-Andersen, 2011).”
- Regulation of cytoplasmic mRNA decay (2012, neutral): “The selective loss of endoplasmic-reticulum-associated mRNAs by RIDD contrasts with the generalized stabilization of the mRNA transcriptome that occurs during oxidative stress or amino acid starvatio”
- Eukaryotic stress granules: the ins and outs of translation. (2009, background): “Stress granules have been hypothesized to function in repression, given that numerous stress granule components are translational repressors and their formation correlates with decreased global translation (Anderson and Kedersha, 2009).”
- Liquid phase condensation in cell physiology and disease (2017, background): “are RNA- and protein-rich, they are variously referred to as “RNA granules” (4), “RNP bodies””
- RNA methylation by Dnmt2 protects transfer RNAs against stress-induced cleavage. (2010, background): “Stress granules and processing bodies contain high numbers of RNA molecules (Anderson and Kedersha 2009), and heat-shock stress responses have been linked to changes in RNA methylation in bacteria (Bugl et al.”
- Principles and Properties of Stress granules (2016, background): “First, stress granules form when translation initiation is inhibited either by drugs or by stress responses [4].”