Results of a Prospective Study of Acute Liver Failure at 17 Tertiary Care Centers in the United States
By G. Ostapowicz, R. Fontana, Frank V. Schioødt, A. Larson, T. Davern, Steven‐Huy B. Han, T. Mccashland, A. Shakil, J. Hay, L. Hynan and 23 more. Annals of Internal Medicine, 2002
2,188 citations recorded by the source corpus.
Subfields: Hepatology, Pharmacology
View Paper: https://www.semanticscholar.org/paper/405069463c77ceba4a71ddf71e6bf4e77a79617f
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In Hepatology
Citations in the corpus
- HLA-B*5701 genotype is a major determinant of drug-induced liver injury due to flucloxacillin (2009, background): “Idiosyncratic hepatotoxicity accounts for 13% of acute liver failure cases in the United States, and 75% of affected individuals either die or require liver transplantatio”
- Idiosyncratic drug hepatotoxicity (2005, background): “DILD is the leading cause of acute liver failure in the United States, accounting for about half of all case”
- Primary Hepatocytes: Current Understanding of the Regulation of Metabolic Enzymes and Transporter Proteins, and Pharmaceutical Practice for the Use of Hepatocytes in Metabolism, Enzyme Induction, Transporter, Clearance, and Hepatotoxicity Studies (2007, background): “More than 600 current drugs have the potential to cause liver injury in man and DILI is increasingly recognized as a major cause of serious illness (including acute fulminant hepatic failure or chronic persistent liver damage that ultimately may require transplantation) (Ostapowicz et al., 2002).”
- Acute liver failure: Summary of a workshop (2007, background): “Current United Network for Organ Sharing (UNOS) criteria for Status 1 listing are (1) onset of any degree of hepatic encephalopathy within 8 weeks of onset of acute liver injury; (2) absence of pre-existing liver disease; (3) life expectancy of less than 7 days; and (4) in the intensive care unit (I”