HLA-B*5701 genotype is a major determinant of drug-induced liver injury due to flucloxacillin
By A. Daly, P. Donaldson, P. Bhatnagar, Yufeng Shen, Itsik Pe'er, A. Floratos, M. J. Daly, David B. Goldstein, Sally John, Matthew R. Nelson and 8 more. Nature Genetics, 2009
1,054 citations recorded by the source corpus.
Subfields: Hepatology, Oncology, Pharmacology
View Paper: https://www.semanticscholar.org/paper/5d35c2fc6c0dc129a328d6ff4d7044aa089e3a43
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Citations in the corpus
- HLA-A★3101 and Carbamazepine-Induced Hypersensitivity Reactions in Europeans (2011, result): “Genomewide approaches are increasingly used to identify genetic predisposing factors for druginduced hypersensitivity reactions and druginduced liver injury.(3) For example, the HLAB*1502 allele has been identified as a clinically important predictor of SJS–TEN in Asians of Han Chinese descent who a”
- RUCAM in Drug and Herb Induced Liver Injury: The Update (2015, methodology): “RUCAM has been used to identify DILI and HILI events in case studies of prescription drugs [8,9,112,172], herbal medications [14,168], regulatory evaluations [81,86–88,90,92,94], epidemiological studies [2,99,113,173], genotyping studies [83,100], phase I clinical studies [154] and long-term post ma”
- Quality Control Procedures for Genome Wide Association Studies (2011, background): “More recently, GWAS are being conducted in cohorts that are clinic-based (Link et al., 2008; Daly et al., 2009; Thompson et al., 2009; Barber et al., 2010).”