RNA editing by adenosine deaminases that act on RNA.

By B. Bass. Annual Review of Biochemistry, 2002

1,258 citations recorded by the source corpus.

View Paper: https://www.semanticscholar.org/paper/404ea893bb77bb7b996583afabe334c2de903612

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Citations in the corpus

Widespread A-to-I RNA Editing of Alu-Containing mRNAs in the Human Transcriptome (2004, background): “…between A-to-I RNA editing and RNAi has recently been suggested through studies in C. elegans where inactivation of the editing machinery leads to transgene silencing (Knight and Bass 2002), and subsequent inactivation of the RNAi pathway restored transgene expression (Tonkin and Bass 2003).”
Modulation of microRNA processing and expression through RNA editing by ADAR deaminases (2006, background): “Three members of the ADAR gene family (ADAR1–3) have been identified in vertebrate”
The cell biology of synaptic plasticity: AMPA receptor trafficking. (2007, background): “AMPARs are also regulated by RNA editing, a process involving enzymatic deamination of ribonucleotides in prespliced mRNA (Bass 2002).”
An Architectural Role for a Nuclear Non-coding RNA: NEAT1 RNA is Essential for the Structure of Paraspeckles (2009, background): “We saw no evidence of significant G substitution in the cDNA clones, which is the hallmark of inosine substitution, nor did our sequence analysis identify any canonical ADAR enzyme targets (reviewed in Bass, 2002).”
Biogenesis and Function of Nuclear Bodies (2011, background): “The deamination of adenosine to inosine (A-to-I) in RNA is catalyzed by members of adenosine deaminase that acts on RNA (ADAR) enzyme family [112].”
Identification of microRNAs of the herpesvirus family (2005, background): “The sequence and structural context of the edited A is optimal for recognition by adenosine deaminases acting on RNA, which prefer a 5′ uracil and a mismatched cytosine on the opposite stran”
RNA-binding proteins: modular design for efficient function (2007, background): “ADARs function instead on dsRNA to catalyse the conversion of adenosine to inosine, which is then recognized as guanosine, affecting both the primary sequence and structure of the edited RN”
Editing modifies the GABAA receptor subunit α3 (2007, background): “However, editing occurs with little sequence specificity in largely double-stranded RNA (Bass 2002).”
Systematic identification of abundant A-to-I editing sites in the human transcriptome (2004, background): “12,723 A-to-I editing sites were mapped in 1,637 different genes, with an estimated accuracy of 95%.”
Sequential action of a tRNA base editor in conversion of cytidine to pseudouridine (2022, background): “59 A-to-I and C-to-U RNA editing are mediated by zinc-dependent deaminases, from the ADAR 60 (adenosine deaminase acting on RNA) (Bass, 2002), ADAT (adenosine deaminase acting on tRNAs) 61”
Glutamate Receptor Ion Channels: Structure, Regulation, and Function (2010, methodology): “The glutamine within the QRN site is converted to arginine by adenosine deaminase (Sommer et al., 1991; Bass, 2002).”